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  • Viral shape-shifting: norovirus evasion of the human immune system.
    We discuss the molecular and structural mechanisms that facilitate the persistence of noroviruses in human populations....
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  • Viral infection: miRNAs help KSHV lay low
    Kaposi's sarcoma-associated herpesvirus (KSHV) establishes a long-term, latent infection in its target cells, during which a limited...
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  • Host interactions of probiotic bacterial surface molecules: comparison with commensals and pathogens.
    We highlight the documented signalling interactions of the surface molecules of probiotic bacteria (such as long surface appendages,...
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  • The population genetics of commensal Escherichia coli.
    We describe the population structure of commensal E. coli, the factors involved in the spread of different strains, how the bacteria...
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  • Regulation of the replication cycle: conserved and diverse regulatory systems for DnaA and oriC.
    We describe the regulation of DnaA, one of the central proteins involved in bacterial DNA replication, by these factors in Escherich...
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  • Symbiosis: Breaking the rhizobial barrier
    Rhizobial bacteria form mutualistic endosymbioses with legumes, in which they induce the formation of root nodules and fix nitrogen....
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  • Taming the next-gen beast.
    This month's Genome Watch discusses how alternative approaches to using second-generation sequencing technologies ar...
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  • Archaea: Singled out from the crowd
    Ubiquitin is a small eukaryotic protein with a characteristic β-grasp fold that can be conjugated to other proteins. In many cases,...
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  • In brief: Virology, Systems biology, Bacterial physiology
    Repulsion of superinfecting virions: a mechanism for rapid virus spread Doceul, V.et al. Science21 Jan 2010 (doi:10.1126/science.1183...
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  • Spectrum of latent tuberculosis - existing tests cannot resolve the underlying phenotypes.
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  • Industrial microbiology: Fuelling the renewable revolution
    The production of fuels and other high-value chemicals through microbial fermentation has the potential to provide a sustainable alte...
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  • In this issue
    The study of the molecular biology of bacteria goes back nearly a century, but some fundamental processes, such as DNA replication an...
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  • Editorial: A birthday gift for GAVI
    The GAVI Alliance was established in 2000 in response to the need to dramatically increase vaccine coverage for children in developin...
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  • The phasevarion: phase variation of type III DNA methyltransferases controls coordinated switching in multiple genes
    In several host-adapted pathogens, phase variation has been found to occur in genes that encode methyltransferases associated with ty...
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  • Bacterial nucleoid-associated proteins, nucleoid structure and gene expression
    Emerging models of the bacterial nucleoid show that nucleoid-associated proteins (NAPs) and transcription contribute in combination t...
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  • Spectrum of latent tuberculosis - existing tests cannot resolve the underlying phenotypes: author's reply.
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  • Parasitology: Epigenetic regulation of VSG expression
    The controversial issue of the chromatin structure at VSG expression site loci in African trypanosomes seems to have been resolved wi...
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  • A complex journey: transmission of microbial symbionts.
    We describe the journey of symbionts from the initial contact to their final residence. We provide an overview of the molecular mech...
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  • In the news.
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  • In brief: Bacterial pathogenicity, Environmental microbiology, Innate immunity
    A type VI secretion system of Pseudomonas aeruginosa targets a toxin to bacteria Hood, R. D.et al. Cell Host Microbe 7, 25–37 (2010...
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