Latest papers

The profilin:actin complex localizes to sites of dynamic actin polymerization at the leading edge of migrating cells and pathogen-induced actin tails.

Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility.

G-actin regulates rapid induction of actin nucleation by mDia1 to restore cellular actin polymers.

Harpooning the Cvt complex to the phagophore assembly site.

Cytoskeletal regulation: coordinating actin and microtubule dynamics in membrane trafficking.

Genetically encoded photoswitching of actin assembly through the Cdc42-WASP-Arp2/3 complex pathway.

EspF Interacts with nucleation-promoting factors to recruit junctional proteins into pedestals for pedestal maturation and disruption of paracellular permeability.

Close packing of Listeria monocytogenes ActA, a natively unfolded protein, enhances F-actin assembly without dimerization.

The Arp2/3 activators WAVE and WASP have distinct genetic interactions with Rac GTPases in Caenorhabditis elegans axon guidance.

WHAMMing into the Golgi.

WHAMM is an Arp2/3 complex activator that binds microtubules and functions in ER to Golgi transport.

WAVE and Arp2/3 jointly inhibit filopodium formation by entering into a complex with mDia2.

Molecular mechanisms of phagocytic uptake in mammalian cells.

Influence of phalloidin on the formation of actin filament branches by Arp2/3 complex.

Actin in the endocytic pathway: from yeast to mammals.

How do in vitro reconstituted actin-based motility assays provide insight into in vivo behavior?

Functional surfaces on the p35/ARPC2 subunit of Arp2/3 complex required for cell growth, actin nucleation, and endocytosis.

Arp2/3 Controls the Motile Behavior of N-WASP-Functionalized GUVs and Modulates N-WASP Surface Distribution by Mediating Transient Links with Actin Filaments

Organization of the Arp2/3 complex in hippocampal spines.

Capping protein increases the rate of actin-based motility by promoting filament nucleation by the Arp2/3 complex.