Latest papers

The role of the Agouti-Related Protein in energy balance regulation.

Central resistin regulates hypothalamic and peripheral lipid metabolism in a nutritional-dependent fashion.

Differential effects of refeeding on melanocortin-responsive neurons in the hypothalamic paraventricular nucleus.

Glucocorticoids increase neuropeptide Y and agouti-related peptide gene expression via adenosine monophosphate-activated protein kinase signaling in the arcuate nucleus of rats.

Synaptic release of GABA by AgRP neurons is required for normal regulation of energy balance.

Estradiol decreases the orexigenic effect of neuropeptide Y, but not agouti-related protein, in ovariectomized rats.

UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals.

Leptin infusion and obesity in mouse cause alterations in the hypothalamic melanocortin system.

Signal transducer and activator of transcription-3 is required in hypothalamic agouti-related protein/neuropeptide Y neurons for normal energy homeostasis.

Modulation of melanocortin signaling ameliorates uremic cachexia.

Hypothalamic neuropeptide expression of juvenile and middle-aged rats after early postnatal food restriction.

Expression of energy balance regulatory genes in the developing ovine fetal hypothalamus at midgestation and the influence of hyperglycemia.

Effects of fluoxetine administration on hypothalamic melanocortin system in obese Zucker rats.

Agouti-related peptide and MC3/4 receptor agonists both inhibit excitatory hypothalamic ventromedial nucleus neurons.

Hypothalamic CaMKK2 contributes to the regulation of energy balance.

The CAMplexities of central ghrelin.

Pharmacological analyses of two naturally occurring porcine melanocortin-4 receptor mutations in domestic pigs.

The melanocortin antagonist AgRP (83-132) increases appetitive responding for a fat, but not a carbohydrate, reinforcer.

Immune activation driven by CTLA-4 blockade augments viral replication at mucosal sites in simian immunodeficiency virus infection.

PYY3-36 injection in mice produces an acute anorexigenic effect followed by a delayed orexigenic effect not observed with other anorexigenic gut hormones.