Latest papers

Response to Protocol Review Scenario: Addition is significant

Amendments for additional animals: not a minor amendment.

Going through the phases.

Going through the phases. Response: Approve and monitor.

More is less: reducing animal use by raising awareness of the principles of efficient study design and analysis.

The FRAME Reduction Steering Committee: reflections on a decade devoted to reducing animal use in biomedical science.

Fifty years after Russell and Burch, toxicologists continue to ignore genetic variation in their test animals.

Worldwide trends in the use of animals in research: the contribution of genetically-modified animal models.

Planning for reduction.

Surgical oocyte retrieval (SOR): a method for collecting mature mouse oocytes without euthanasia.

American College of Toxicology: Policy statement on the use of animals in toxicology.

The need for realism in reproductive toxicity testing.

Animal experimentation: weighing the benefits against the suffering.

Switching swine for simulators: at what cost?

Successful prevalidation of the slug mucosal irritation test to assess the eye irritation potency of chemicals.

Medical schools swap pigs for plastic.

Mucosal irritation potential of personal lubricants relates to product osmolality as detected by the slug mucosal irritation assay.

[Importance of research on alternatives to animal experiments in pharmaceutical sciences].

Pushing the limits.

[Alternatives to animal experimentation v.s. animal rights terrorism].