Latest papers

The evaluation of some pharmaceutically acceptable excipients as permeation enhancers for amoxicillin.

[Molecular mechanism in biological transport in the kidney: Urate transporter URAT1].

Phenothiazine maleates stimulate MRP1 transport activity in human erythrocytes.

Involvement of uric acid transporter in increased renal clearance of the xanthine oxidase inhibitor oxypurinol induced by a uricosuric agent, benzbromarone.

Prediction of CYP2C9-mediated drug-drug interactions: a comparison using data from recombinant enzymes and human hepatocytes.

CYP2C9 genotype-dependent effects on in vitro drug-drug interactions: switching of benzbromarone effect from inhibition to activation in the CYP2C9.3 variant.

Benzbromarone therapy in management of refractory gout.

Optimal management of chronic gout: attempting to render the (t)issues crystal-clear.

Mechanisms of benzarone and benzbromarone-induced hepatic toxicity.

Charge and substituent effects on affinity and metabolism of benzbromarone-based CYP2C19 inhibitors.

The efficacy of combined low dose of Allopurinol and benzbromarone compared to standard dose of Allopurinol in hyperuricemia.

Spinal tophaceous gout mimicking a spinal tumor.

Quantitative binding models for CYP2C9 based on benzbromarone analogues.

Multidrug resistance protein 4 (MRP4/ABCC4) mediates efflux of bimane-glutathione.

[Chronic gout. Case report of a severe course of disease].

Multidrug resistance protein-6 (MRP6) in human dermal fibroblasts. Comparison between cells from normal subjects and from Pseudoxanthoma elasticum patients.

Stopping progression in familial juvenile hyperuricemic nephropathy with benzbromarone?

A new class of CYP2C9 inhibitors: probing 2C9 specificity with high-affinity benzbromarone derivatives.

A case of exercise-induced acute renal failure in a patient with idiopathic renal hypouricemia developed during antihypertensive therapy with losartan and trichlormethiazide.

Effects of aspirin and/or salicylate on hydrolysis and glucuronidation of indomethacin in rat erythrocytes and hepatocytes.