Latest papers

Nicotinic receptor-mediated reduction in L-DOPA-induced dyskinesias may occur via desensitization.

The p53 tumor suppressor: A master regulator of diverse cellular processes and therapeutic target in cancer

The first diastereoselective synthesis of cinerins A-C, PAF-antagonistic macrophyllin-type bicyclo[3.2.1]octane neolignans, using a novel Pd-catalysed oxyarylation.

The mGluR2/3 agonist LY379268 blocks the effects of GLT-1 upregulation on prepulse inhibition of the startle reflex in adult rats.

Computational analysis of the binding ability of heterocyclic and conformationally constrained epibatidine analogs in the neuronal nicotinic acetylcholine receptor.

The glutamatergic compounds sarcosine and N-acetylcysteine ameliorate prepulse inhibition deficits in metabotropic glutamate 5 receptor knockout mice.

Interfacing conjugated polymers with magnetic nanowires.

Encapsulation of recombinant E. coli expressing cyclopentanone monooxygenase in polyelectrolyte complex capsules for Baeyer-Villiger biooxidation of 8-oxabicyclo[3.2.1]oct-6-en-3-one.

Latrunculin A dramatically improves the developmental capacity of nuclear transfer embryos derived from gene-modified clawn miniature pig cells.

Characterization of an aggregation pheromone in Hylesinus pruinosus (Coleoptera: Curculionidae: Scolytinae).

F-actin dynamics in Neurospora crassa.

Actin reorganization underlies phototropin-dependent positioning of nuclei in Arabidopsis leaf cells.

Thiochroman derivative CH4986399, a new nonsteroidal estrogen receptor down-regulator, is effective in breast cancer models.

LGP1, A histone deacetylase inhibitor analogue of FR235222, sensitizes promyelocytic leukaemia U937 cells to TRAIL-mediated apoptosis.

Activation of metabotropic glutamate (mGlu)2 receptors suppresses histamine release in limbic brain regions following acute ketamine challenge.

Incorporation of collagen in poly(3,4-ethylenedioxythiophene) for a bifunctional film with high bio- and electrochemical activity.

Chrna4 A529 knock-in mice exhibit altered nicotine sensitivity.

NBBA, a synthetic small molecule, inhibits TNF-alpha-induced angiogenesis by suppressing the NF-kappaB signaling pathway.

Investigations into the binding affinities of different human 5-HT4 receptor splice variants.

Statins and the squalene synthase inhibitor zaragozic acid stimulate the non-amyloidogenic pathway of amyloid-beta protein precursor processing by suppression of cholesterol synthesis.