Latest papers

Discovery of a competitive apelin receptor (APJ) antagonist.

Construction and modelling of an inducible positive feedback loop stably integrated in a mammalian cell-line.

Identification and relative quantitation of an orphan G-protein coupled receptor SREB2 (GPR85) protein in tissue using a linear ion trap mass spectrometer.

Preclinical screening of anti-HER2 nanobodies for molecular imaging of breast cancer.

[Construction and expression of the eukaryotic expression vector carrying HSV-1 gC glycoprotein gene].

Effectiveness of a Chinese hamster ovary cell derived hepatitis B vaccine in Chinese rural communities.

Comparability and monitoring immunogenic N-linked oligosaccharides from recombinant monoclonal antibodies from two different cell lines using HPLC with fluorescence detection and mass spectrometry.

Potent macrocyclic inhibitors of insulin-regulated aminopeptidase (IRAP) by olefin ring-closing metathesis.

Reorganization of the actin cytoskeleton upon G-protein coupled receptor signaling

Binding of cell-penetrating penetratin peptides to plasma membrane vesicles correlates directly with cellular uptake

Design, synthesis, and characterization of a single-chain peptide antagonist for the relaxin-3 receptor RXFP3.

Cleavage-resistant fusion proteins of the M(2) muscarinic receptor and Gα(i1). Homotropic and heterotropic effects in the binding of ligands.

Mechanism of protection of bystander cells by exogenous carbon monoxide: impaired response to damage signal of radiation-induced bystander effect.

An improved method for specific and quantitative determination of the clopidogrel active metabolite isomers in human plasma.

Bleeding tendency and impaired platelet function in a patient carrying a heterozygous mutation in the thromboxane A2 receptor. LID - 10.1111/j.1538-7836.2011.04245.x [doi]

Attenuation of the lysosomal death pathway by lysosomal cholesterol accumulation.

Cross-reactivity of outer membrane proteins of Campylobacter species with cholera toxin.

Application of a high-throughput screening procedure with PEG-induced precipitation to compare relative protein solubility during formulation development with IgG1 monoclonal antibodies. LID - 10.1002/jps.22350 [doi]

Surface modification with fibrin/hyaluronic acid hydrogel on solid-free form-based scaffolds followed by BMP-2 loading to enhance bone regeneration.

Curcumin and Alzheimer disease: this marriage is not to be performed.