Latest papers

Mechanism of ubiquitylation by dimeric RING ligase RNF4.

Simultaneous visualization of the extracellular and cytoplasmic domains of the epidermal growth factor receptor.

Reversibility and efficiency in electrocatalytic energy conversion and lessons from enzymes.

The structural basis of RNA-catalyzed RNA polymerization.

The structure of the kinesin-1 motor-tail complex reveals the mechanism of autoinhibition.

High-speed atomic force microscopy reveals rotary catalysis of rotorless F₁-ATPase.

Biochemistry. Seeing a molecular motor at work.

Nucleotide docking: prediction of reactant state complexes for ribonuclease enzymes.

Oxime-based click chemistry in the development of 3-isoxazolecarboxylic acid containing inhibitors of Yersinia pestis protein tyrosine phosphatase, YopH.

Nucleotide docking: prediction of reactant state complexes for ribonuclease enzymes.

Enzymatic characterization and molecular modeling of an evolutionarily interesting fungal β-N-acetylhexosaminidase

Molecular mechanism for eliminylation, a newly discovered post-translational modification.

Selection of the most potent specific on/off adaptor-hepatitis delta virus ribozymes for use in gene targeting.

Understanding the HIV-1 protease reactivity with DFT: what do we gain from recent functionals?

An RNA-induced conformational change required for CRISPR RNA cleavage by the endoribonuclease Cse3.

The N-terminus of the RNA polymerase from infectious pancreatic necrosis virus is the determinant of genome attachment.

Mechanistic rationale for inhibition of poly(ADP-ribose) polymerase in ETS gene fusion-positive prostate cancer.

Pressure-response analysis of anesthetic gases xenon and nitrous oxide on urate oxidase: a crystallographic study.

On the mechanism of dimethylarginine dimethylaminohydrolase inactivation by 4-halopyridines.

Competition between Li+ and Mg2+ in metalloproteins. Implications for lithium therapy.