Latest papers

GSK-3 inhibitors and insulin receptor signaling in health, disease, and therapeutics.

Chromaffin cells in the amphibian urodele Triturus carnifex show ultrastructural features indicative of a vesicle-mediated mode of cell degranulation.

Drug development targeting the glycogen synthase kinase-3beta (GSK-3beta)-mediated signal transduction pathway: the role of GSK-3beta in the maintenance of steady-state levels of insulin receptor signaling molecules and Na(v)1.7 sodium channel in adrenal chromaffin cells.

The Voltage-Gated Ca2+ Channel Is the Ca2+ Sensor Protein of Secretion

The chromaffin vesicle: advances in understanding the composition of a versatile, multifunctional secretory organelle.

Cell therapy for pain.

Secretory vesicle rebound hyperacidification and increased quantal size resulting from prolonged methamphetamine exposure.

A low nicotine concentration augments vesicle motion and exocytosis triggered by K(+) depolarisation of chromaffin cells.

Characterization of catecholamine release from deer adrenal medullary chromaffin cells.

Glucosensing in an immortalized adrenomedullary chromaffin cell line: role of ATP-sensitive K+ channels.

G protein betagamma subunits modulate the number and nature of exocytotic fusion events in adrenal chromaffin cells independent of calcium entry.

The role of the C terminus of the SNARE protein SNAP-25 in fusion pore opening and a model for fusion pore mechanics.

Magnetron sputtered diamond-like carbon microelectrodes for on-chip measurement of quantal catecholamine release from cells.

Nongenomic glucocorticoid effects on activity-dependent potentiation of catecholamine release in chromaffin cells.

Human follicle-stimulating hormone modulation of adrenal gland activity in the Italian crested newt, Triturus carnifex (Amphibia, Urodela).

A random mutagenesis approach to isolate dominant-negative yeast sec1 mutants reveals a functional role for domain 3a in yeast and mammalian Sec1/Munc18 proteins.

Dynamin I plays dual roles in the activity-dependent shift in exocytic mode in mouse adrenal chromaffin cells.

A fast mode of membrane fusion dependent on tight SNARE zippering.

Automated analysis of secretory vesicle distribution at the ultrastructural level.

Regulation of quantal shape by Rab3A: evidence for a fusion pore-dependent mechanism.