Latest papers

JNK inhibition arrests cotranslational degradation.

In situ fluorescence imaging of myelination.

A peptide-based fluorescent ratiometric sensor for quantitative detection of proteins.

PI3K/Akt signaling transduction pathway is involved in rat vascular smooth muscle cell proliferation induced by apelin-13.

Synthesis and evaluation of novel chromone analogs for their inhibitory activity against interleukin-5.

Cochliones A-D, four new tetrahydrochromanone derivatives from endophytic Cochliobolus sp.

[Effects of insulin and LY294002 inhibitors of PI3K on the regulations and expression of aquaporin 9 in normal liver cells].

Activation of FOXO3a is sufficient to reverse mitogen-activated protein/extracellular signal-regulated kinase kinase inhibitor chemoresistance in human cancer.

Survivin transcription is associated with P-glycoprotein/MDR1 overexpression in the multidrug resistance of MCF-7 breast cancer cells.

Leucine-rich glioma inactivated 3 induces neurite outgrowth through Akt and focal adhesion kinase.

Chromone-2- and -3-carboxylic acids inhibit differently monoamine oxidases A and B.

Anti-apoptotic effects of human granulocyte colony-stimulating factor (G-CSF) on retinal ganglion cells after optic nerve crush are PI3K/AKT-dependent.

Synthesis of a novel series of diphenolic chromone derivatives as inhibitors of NO production in LPS-activated RAW264.7 macrophages.

Rapamycin promotes the osteoblastic differentiation of human embryonic stem cells by blocking the mTOR pathway and stimulating the BMP/Smad pathway.

A C(2)-symmetric chiral bis-sulfoxide ligand in a rhodium-catalyzed reaction: asymmetric 1,4-addition of sodium tetraarylborates to chromenones.

Targeting the cell cycle and the PI3K pathway: a possible universal strategy to reactivate innate tumor suppressor programmes in cancer cells.

Chemical constituents of Baeckea frutescens leaves inhibit copper-induced low-density lipoprotein oxidation.

Nicotine induces resistance to chemotherapy in nasal epithelial cancer.

Rapid and quantitative detection of Legionella pneumophila applying immunomagnetic separation and flow cytometry.

Expression of hypoxia-inducible factor 1 alpha in thyroid carcinomas.