Latest papers

Design and experimental validation of a generic model for combinatorial assembly of DNA tiles into 1D-structures.

Copper-catalyzed domino synthesis of quinazolinones via Ullmann-type coupling and aerobic oxidative C-H amidation.

A new class of urea-substituted cinchona alkaloids promote highly enantioselective nitroaldol reactions of trifluoromethylketones.

Enantioselective synthesis of a GPR40 agonist AMG 837 via catalytic asymmetric conjugate addition of terminal alkyne to α,β-unsaturated thioamide.

Fungal cyclooligomer depsipeptides: from classical biochemistry to combinatorial biosynthesis.

Combinatorial library design from reagent pharmacophore fingerprints.

Molecular library design using multi-objective optimization methods.

Design of screening collections for successful fragment-based lead discovery.

GLARE: A tool for product-oriented design of combinatorial libraries.

CLEVER: A general design tool for combinatorial libraries.

A scalable approach to combinatorial library design.

Spatially addressed combinatorial protein libraries for recombinant antibody discovery and optimization.

Fluorous diastereomeric mixture synthesis (FDMS) of hydantoin-fused hexahydrochromeno[4,3-b]pyrroles.

Discovery of novel cell proliferation-enhancing gene by random siRNA library based combinatorial screening.

High-throughput analysis of protein stability in polyanhydride nanoparticles.

A convenient and robust method for construction of combinatorial and random mutant libraries.

Organocatalytic enantioselective olefin aminofluorination.

Studies on the biodistribution of dextrin nanoparticles.

Boron-based dipolar multicomponent reactions: simple generation of substituted aziridines, oxazolidines and pyrrolidines.

Total synthesis of (+/-)-marinopyrrole A and its library as potential antibiotic and anticancer agents.