Latest papers

RHP is antigenically related to factor H and binds to the globular heads of C1q.

Complement activation in the follicular light zone of human lymphoid tissues.

Short amino acid sequences derived from C1q receptor (C1q-R) show homology with the alpha chains of fibronectin and vitronectin receptors and collagen type IV.

Smooth muscle and epithelial cells express specific binding sites for the C1q component of complement.

Platelet interactions with C1q in whole blood and in the presence of immune complexes or aggregated IgG.

Recombinant mouse monoclonal antibodies with single amino acid substitutions affecting Clq and high affinity Fc receptor binding have identical serum half-lives in the BALB/c mouse.

Mannan-binding protein, a complement activating animal lectin.

Effects of excess factor D on early- and late-phase activation of the complement cascade.

Human anti-idiotypic antibody responses to autoantibody against the alternative pathway C3 convertase.

Human leukocyte C1q receptor binds other soluble proteins with collagen domains.

Localization of the covalent C3b-binding site on C4b within the complement classical pathway C5 convertase, C4b2a3b.

Inhibition of the alternative C3 convertase and classical C5 convertase of complement by group A streptococcal M protein.

Molecular and functional identification and purification of complement component factor D from urine of patients with chronic renal failure.

Evidence that production of autoantibody to the alternative pathway C3 convertase is a normal physiologic event.

Autoantibody to complement neoantigens in membranoproliferative glomerulonephritis.

A monoclonal antibody which blocks the function of factor D of human complement.

Peptide inhibitors of C3 breakdown.

Monoclonal anti-human C3d antibodies: stabilization of the alternative pathway C3 convertase.

Complete and partial deficiencies of complement factor D in a Dutch family.

Murine membrane inhibitor of complement which accelerates decay of human C3 convertase.