Latest papers

Crystal structure, DNA binding studies, nucleolytic property and topoisomerase I inhibition of zinc complex with 1,10-phenanthroline and 3-methyl-picolinic acid.

C-lysine conjugates: pH-controlled light-activated reagents for efficient double-stranded DNA cleavage with implications for cancer therapy.

A zinc site in the C-terminal domain of RAG1 is essential for DNA cleavage activity.

The structure-based design, synthesis, and biological evaluation of DNA-binding amide linked bisintercalating bisanthrapyrazole anticancer compounds

Linear disulfide-containing low polymer as efficient DNA cleavage reagent

Synthesis and DNA cleavage activity of 2-hydrazinyl-1,4,5,6-tetrahydropyrimidine containing hydroxy group

AdnAB: a new DSB-resecting motor–nuclease from mycobacteria

Synthesis, X-ray crystal structures, magnetism, and DNA cleavage properties of copper(II) complexes with 1,4-tpbd ligand.

Synthesis of a novel linear polymer of a macrocyclic polyamine copper (II) complex and its interaction with plasmid DNA.

Synthesis, structure, magnetic properties and DNA cleavage of binuclear Cu(II) Schiff-base complexes.

Iron(III)-salen complexes with less DNA cleavage activity exhibit more efficient apoptosis in MCF7 cells.

Synthesis, characterization, DNA-binding, and DNA-photocleavage properties of [Co(bpy)2(7-NO2-dppz)]3+, [Co(dmb)2(7-NO2-dppz)]3+, and [Co(phen)2(7-NO2-dppz)]3+ complexes: (7-nitro-dppz = 7-nitro dipyrido[3,2-a:2'-3'-c]phenazine; bpy = 2,2'-bipyridine; dmb = 4,4'-dimethyl-2,2'-bipyridine; phen = 1,10-phenanthroline) and their toxicity on different microorganisms.

DNA-binding and cleavage studies of a novel two-dimensional manganese(II) azide complex with N-methylimidazole.

DNA binding and oxidative DNA cleavage activity of (mu-oxo)diiron(iii) complexes in visible light.

Initiation of DNA strand cleavage by 1,2,4-benzotriazine 1,4-dioxide antitumor agents: mechanistic insight from studies of 3-methyl-1,2,4-benzotriazine 1,4-dioxide.

DNA binding and cleavage properties of ponicidin.

Cleavage of plasmid DNA by eukaryotic topoisomerase II.

HMGB1/2 can target DNA for illegitimate cleavage by the RAG1/2 complex.

Toxicity of copper(I)-NHC complexes against human tumor cells: induction of cell cycle arrest, apoptosis, and DNA cleavage.

Binding and photocleavage of DNA by mixed ligand Co(III) and Ni(II) complexes of thiophene[2, 3-b] quinoline and phenanthrolie/bipyridine.