Latest papers

The relevance of oxidative stress and cytotoxic DNA lesions for spontaneous mutagenesis in non-replicating yeast cells.

Function of Apollo (SNM1B) at telomere highlighted by a splice variant identified in a patient with Hoyeraal-Hreidarsson syndrome.

Gene expression profiling predicts response to temozolomide in malignant gliomas.

5-Aza-2'-deoxycytidine is a potent inhibitor of DNA methyltransferase 3B and induces apoptosis in human endometrial cancer cell lines with the up-regulation of hMLH1.

Prognostic value of O6-methylguanine-DNA methyltransferase status in glioblastoma patients, assessed by five different methods.

Some common mutations of RAD50 and NBS1 in western populations do not contribute significantly to Chinese non-BRCA1/2 hereditary breast cancer.

Primary CNS lymphoma in the elderly: temozolomide therapy and MGMT status.

Suppression of mutagenesis by 8-hydroxy-2'-deoxyguanosine 5'-triphosphate (7,8-dihydro-8-oxo-2'-deoxyguanosine 5'-triphosphate) by human MTH1, MTH2, and NUDT5.

The SbcCD complex of Deinococcus radiodurans contributes to radioresistance and DNA strand break repair in vivo and exhibits Mre11-Rad50 type activity in vitro.

Polymorphisms of the DNA repair gene MGMT and risk and progression of head and neck cancer.

Changes of the O6-methylguanine-DNA methyltransferase promoter methylation and MGMT protein expression after adjuvant treatment in glioblastoma.

A divalent FHA/BRCT-binding mechanism couples the MRE11-RAD50-NBS1 complex to damaged chromatin.

A phase II trial of primary temozolomide in patients with grade III oligodendroglial brain tumors.

Prognostic markers in gliomas.

Three-dimensionally specific inhibition of DNA repair-related genes by activated KRAS in colon crypt model.

Aberrant gene methylation in the lymph nodes provides a possible marker for diagnosing micrometastasis in gastric cancer.

Physical interaction between the histone acetyl transferase Tip60 and the DNA double-strand breaks sensor MRN complex.

Microsatellite instability in colorectal cancer-the stable evidence.

Mutations in PNKP cause microcephaly, seizures and defects in DNA repair.

Emodin, aloe-emodin and rhein induced DNA damage and inhibited DNA repair gene expression in SCC-4 human tongue cancer cells.