Latest papers

Long-term prospective randomised clinical and manometric comparison between surgical and chemical sphincterotomy for treatment of chronic anal fissure.

[Successful treatment of polymedicamentous poisoning with metoprolol, diltiazem and cilazapril].

Recurrent ventricular fibrillation due to coronary artery spasm immediately after ascending aorta replacement.

[Diltiazem-induced acute generalized exanthemic pustulosis: a case and review of the literature].

Capecitabine-induced cardiotoxicity: when to suspect? How to manage? A case report.

Influence of grapefruit juice on the pharmacokinetics of diltiazem in Wistar rats upon single and multiple dosage regimens.

Application of a novel symmetrical shape factor to gastroretentive matrices as a measure of swelling synchronization and its impact on drug release kinetics under standard and modified dissolution conditions.

Ask the doctor. After being diagnosed with high blood pressure several years ago, I started taking diltiazem and Atacand. The results were good, giving me an average blood pressure of 110/65. I recently developed gastroenteritis and aspiration pneumonia. While I was in the hospital, my blood pressure got so low I was told to stop taking these medications. I have been off them since, and my blood pressure has remained normal, averaging 105/65. How can this be? Will high blood pressure return?

Acute vasodilator testing in idiopathic pulmonary arterial hypertension: must we take NO for the answer?

Effect of hesperidin on the oral pharmacokinetics of diltiazem and its main metabolite, desacetyldiltiazem, in rats.

A role for the Val291 residue within the transmembrane domain 2 in diltiazem- and TMB-8 [3,4,5-trimethoxybenzoic acid 8-(diethylamino)octyl ester]-mediated 5-hydroxytryptamine type 3A receptor regulations.

ECG of the month. Atrial flutters.

Diltiazem, a L-type Ca(2+) channel blocker, also acts as a pharmacological chaperone in Gaucher patient cells.

[Nephrotoxicity of tacrolimus and preventive effect of diltiazem: experiment with rats].

Effect of genetic polymorphisms of CYP3A5 and MDR1 on cyclosporine concentration during the early stage after renal transplantation in Chinese patients co-treated with diltiazem.

Supraventricular tachycardia.

Arrhythmogenic actions of the Ca2+ channel agonist FPL-64716 in Langendorff-perfused murine hearts.

Effects of metoprolol and diltiazem on plasma homocysteine levels in patients with isolated coronary artery ectasia.

Development and release mechanism of diltiazem HCl prolonged release matrix tablets.

Role of Ca2+ mobilization and Ca2+ sensitization in 8-iso-PGF 2 alpha-induced contraction in airway smooth muscle.