Latest papers

Rigid dipeptide mimics: synthesis of enantiopure C6-functionalized pyrrolizidinone amino acids.

Novel high-throughput electrochemiluminescent assay for identification of human tyrosyl-DNA phosphodiesterase (Tdp1) inhibitors and characterization of furamidine (NSC 305831) as an inhibitor of Tdp1.

Co-administration of Na-EDTA and Diminazene Aceturate (DA) to Mice Infected with DA-resistant Trypanosoma brucei

Genotypic and phenotypic characterization of Trypanosoma brucei gambiense isolates from Ibba, South Sudan, an area of high melarsoprol treatment failure rate.

Combined contribution of TbAT1 and TbMRPA to drug resistance in Trypanosoma brucei

Confirmation of diminazene diaceturate in bovine plasma using electrospray liquid chromatography-mass spectrometry.

SSCP analysis of the P2 purine transporter TcoAT1 gene of Trypanosoma congolense leads to a simple PCR-RFLP test allowing the rapid identification of diminazene resistant stocks.

Study on the susceptibility of Sahel goats to experimental Trypanosoma vivax infection.

Quantitative analysis of DNA-porphyrin interactions.

Drug-resistance of Trypanosoma b. rhodesiense isolates from Tanzania.

Leishmania donovani: differential activities of classical topoisomerase inhibitors and antileishmanials against parasite and host cells at the level of DNA topoisomerase I and in cytotoxicity assays.

The effectivity analysis of accumulation of liposomal, micellar, and water-soluble forms of diminazene in cells and in organs.

A diminazene-resistant strain of Trypanosoma brucei brucei isolated from a dog is cross-resistant to pentamidine in experimentally infected albino rats.

The susceptibility of Trypanosoma congolense isolated in Zambézia Province, Mozambique, to isometamidium chloride, diminazene aceturate and homidium chloride.

Comparative application of wavelet approaches to absorption and ratio spectra for the simultaneous determination of diminazene aceturate and phenazone in veterinary granules for injection.

Diminazene aceturate resistance on the virulence of Trypanosoma brucei for rats.

Thermodynamic evaluation and modeling of proton and water exchange associated with benzamidine and berenil binding to beta-trypsin.

Acquired resistance to berenil in a cloned isolate of Trypanosoma evansi is associated with upregulation of a novel gene, TeDR40.

The pharmacokinetics of diminazene aceturate after intramuscular administration in healthy dogs.

Susceptibility of West African Dwarf goats and WAD x Saanen crosses to experimental infection with Trypanosoma congolense.