Latest papers

Supplemental studies for cardiovascular risk assessment in safety pharmacology: a critical overview.

Tissue dynamics spectroscopy for three-dimensional tissue-based drug screening.

Topological virtual screening: a way to find new compounds active in ulcerative colitis by inhibiting NF-κB.

[Application of pre-clinical PET imaging for drug development].

Development of a method to consistently quantify the structural distance between scaffolds and to assess scaffold hopping potential.

REPROVIS-DB: a benchmark system for ligand-based virtual screening derived from reproducible prospective applications.

[Screen for natural benzylisoquinoline alkaloids against tumor].

Preclinical evaluation of juvenile toxicity.

Synthesis, anticonvulsant and neurotoxicity screening of some novel 1,2,4-trisubstituted-1H-imidazole derivatives.

Design and evaluation of a bioadhesive film for transdermal delivery of propranolol hydrochloride.

[Establishment and application of co-transfection screening method for phytoestrogen active constituents].

Design and evaluation of a bioadhesive film for transdermal delivery of propranolol hydrochloride.

Metformin promotes progesterone receptor expression via inhibition of mammalian target of rapamycin (mTOR) in endometrial cancer cells. LID - 10.1016/j.jsbmb.2010.12.006 [doi]

Benzoxaboroles: a new class of potential drugs for human African trypanosomiasis.

Nanomedicine-nanoemulsion formulation improves safety and efficacy of the anti-cancer drug paclitaxel according to preclinical assessment.

Protective and curative effects of the 15 KD isolated protein from the Peganum harmala L. seeds against carbon tetrachloride induced oxidative stress in brain, tests and erythrocytes of rats.

From bench to clinic: bridging the translational gap in neglected disease drug development.

Catechol, a bioactive degradation product of salicortin, reduces TNF-alpha induced ICAM-1 expression in human endothelial cells.

Anti lipid peroxidation activity of Piper trioicum Roxb. and Physalis minima L. extracts.

Mepolizumab in eosinophilic disorders.