Latest papers

High-performance liquid chromatography analysis of a novel small-molecule, anti-cancer drug, Palomid 529, in human and mouse plasma and in mouse tissue homogenates.

Development of a quantification method for digoxin, a typical P-glycoprotein probe in clinical and non-clinical studies, using high performance liquid chromatography–tandem mass spectrometry: The usefulness of negative ionization mode to avoid competitive adduct-ion formation

Stability of serum carotene at various light and temperature conditions.

Direct monitoring of drug degradation by easy ambient sonic-spray ionization mass spectrometry: the case of enalapril.

Antisense therapy and emerging applications for the management of dyslipidemia

An integrated drug-likeness study for bicyclic privileged structures: from physicochemical properties to in vitro ADME properties.

AmbiOnp: solid lipid nanoparticles of amphotericin B for oral administration.

UV derivative spectrophotometric and RP-HPLC methods for determination of imidapril hydrochloride in tablets and for its stability assessment in solid state.

Determination of sodium metabisulfite in parenteral formulations by HPIC with suppressed conductivity detection.

Kinetics of omeprazole degradation in solid state.

Effect of polymer structure on micelles formed between siRNA and cationic block copolymer comprising thiols and amidines.

Magnetic carbon nanotubes with particle-free surfaces and high drug loading capacity.

Molecular dynamics simulation and binding energy calculation for estimation of oligonucleotide duplex thermostability in RNA-based therapeutics.

Metabolic and pharmacokinetic studies of curcumin, demethoxycurcumin and bisdemethoxycurcumin in mice tumor after intragastric administration of nanoparticle formulations by liquid chromatography coupled with tandem mass spectrometry.

Development and validation of highly sensitive method for determination of misoprostol free acid in human plasma by liquid chromatography–electrospray ionization tandem mass spectrometry: Application to a clinical pharmacokinetic study

Stability of amoxicillin in portable pumps is drug concentration dependent.

Simultaneous free and glycosylated pyridinium crosslink determination in urine: validation of an HPLC-fluorescence method using a deoxypyridinoline homologue as internal standard.

Determination of carboplatin in human plasma using HybridSPE-precipitation along with liquid chromatography-tandem mass spectrometry.

Analysis of imatinib in bone marrow and plasma samples of chronic myeloid leukaemia patients using solid phase extraction LC-ESI-MS.

Stability evaluation of tramadol enantiomers using a chiral stability-indicating capillary electrophoresis method and its application to pharmaceutical analysis. LID - 10.1002/jssc.201100021 [doi]