Latest papers

The role of the Fanconi anemia network in the response to DNA replication stress.

Protein–protein interactions as therapeutic targets in neuropsychopharmacology

Mechanistic insight into site-restricted monoubiquitination of FANCD2 by Ube2t, FANCL, and FANCI.

Oxidative stress in Fanconi anemia hematopoiesis and disease progression.

Altered Nrf2/Keap1-Bach1 equilibrium in pulmonary emphysema.

Kinetic analysis of interaction of BRCA1 tandem breast cancer c-terminal domains with phosphorylated peptides reveals two binding conformations.

HES1 is a novel interactor of the Fanconi anemia core complex.

Spotlight.

Coordinate regulation of Fanconi anemia gene expression occurs through the Rb/E2F pathway.

Genomic stability: FANCJ-dependent G4 DNA repair.

Expression of the BRCA1-interacting protein Brip1/BACH1/FANCJ is driven by E2F and correlates with human breast cancer malignancy.

Mutagenic capacity of endogenous G4 DNA underlies genome instability in FANCJ-defective C. elegans.

[Fanconi anemia and genomic instability].

FANCM of the Fanconi anemia core complex is required for both monoubiquitination and DNA repair.

FANCJ helicase defective in Fanconia anemia and breast cancer unwinds G-quadruplex DNA to defend genomic stability.

Cell cycle-dependent chromatin loading of the Fanconi anemia core complex by FANCM/FAAP24.

Relevance of the Fanconi anemia pathway in the response of human cells to trabectedin.

Fanconi anemia is a highly penetrant cancer susceptibility syndrome.

Cancer risks in Fanconi anemia: findings from the German Fanconi Anemia Registry.

DOG-1 is the Caenorhabditis elegans BRIP1/FANCJ homologue and functions in interstrand cross-link repair.