Latest papers

Altered expression and subcellular distribution of GRK subtypes in the dopamine-depleted rat basal ganglia is not normalized by l-DOPA treatment.

beta2-adrenergic receptor signaling and desensitization elucidated by quantitative modeling of real time cAMP dynamics.

Beta-arrestins: multifunctional cellular mediators.

Characterization of G-protein coupled receptor kinase interaction with the neurokinin-1 receptor using bioluminescence resonance energy transfer.

Pharmacogenomics of G protein-coupled receptor signaling: insights from health and disease.

Amino acid residues in GRK1/GRK7 responsible for interaction with S-modulin/recoverin.

RGS14 prevents morphine from internalizing Mu-opioid receptors in periaqueductal gray neurons.

Arrestins and spinophilin competitively regulate Na+,K+-ATPase trafficking through association with a large cytoplasmic loop of the Na+,K+-ATPase.

Plasma membrane and nuclear localization of G protein coupled receptor kinase 6A.

G protein-coupled receptor kinase 6 controls chronicity and severity of dextran sodium sulphate-induced colitis in mice.

Seven transmembrane receptors: something old, something new.

Differential regulation of the signaling and trafficking of the two prostaglandin D2 receptors, prostanoid DP receptor and CRTH2.

G protein-coupled receptor kinase 2-mediated phosphorylation of downstream regulatory element antagonist modulator regulates membrane trafficking of Kv4.2 potassium channel.

A third photoreceptor-specific GRK found in the retina of Oryzias latipes (Japanese killifish).

Knock-out mice reveal the contributions of P2Y and P2X receptors to nucleotide-induced Ca2+ signaling in macrophages.

Arrestin-2 and G protein-coupled receptor kinase 5 interact with NFkappaB1 p105 and negatively regulate lipopolysaccharide-stimulated ERK1/2 activation in macrophages.

GRK1 and GRK7: unique cellular distribution and widely different activities of opsin phosphorylation in the zebrafish rods and cones.

G-protein-coupled receptor kinase specificity for beta-arrestin recruitment to the beta2-adrenergic receptor revealed by fluorescence resonance energy transfer.

The structure of G protein-coupled receptor kinase (GRK)-6 defines a second lineage of GRKs.

Defective vasodilatory mechanisms in hypertension: a G-protein-coupled receptor perspective.