Latest papers

Long-term persistence of a polyclonal T cell repertoire after gene therapy for X-linked severe combined immunodeficiency.

Molecular dynamics simulation and binding energy calculation for estimation of oligonucleotide duplex thermostability in RNA-based therapeutics.

Biodegradable particulate delivery of vascular endothelial growth factor plasmid from polycaprolactone/polyethylenimine electrospun nanofibers for the treatment of myocardial infarction.

The NFκB pathway: a therapeutic target in glioblastoma.

RNA-mediated restoration of mitochondrial function in cells harboring a Kearns Sayre Syndrome mutation.

Gene therapy for mesothelioma.

[Applications of DNA transposons to the study of gene function in mice].

Non-viral nucleic acid delivery: key challenges and future directions.

Inhibition of invasion and metastasis of MHCC97H cells by expression of snake venom cystatin through reduction of proteinases activity and epithelial-mesenchymal transition.

Case report of extensive metabolism by aldehyde oxidase in humans: Pharmacokinetics and metabolite profile of FK3453 in rats, dogs, and humans

Intradermal vaccinations with RNA coding for TAA generate CD8+ and CD4+ immune responses and induce clinical benefit in vaccinated patients.

Generation of replication-competent and -defective HSV vectors.

[Advances and perspectives in artificial chromosomes].

Efficacy assessment of interferon-alpha-engineered mesenchymal stromal cells in a mouse plasmacytoma model.

[Construction of a shuttle plasmid encoding a chimeric gene of eglA p-Her2/neu ECD-IL-12].

Gene therapy for allergic airway diseases.

Prevention of radiation-induced salivary hypofunction following hKGF gene delivery to murine submandibular glands.

Development of B-lineage predominant lentiviral vectors for use in genetic therapies for B cell disorders.

Controlled extracellular matrix degradation in breast cancer tumors improves therapy by trastuzumab.

HSV delivery of a ligand-regulated endogenous ion channel gene to sensory neurons results in pain control following channel activation.