Latest papers

Sensitive determination of a glyoxal-DNA adduct biomarker candidate by column switching capillary liquid chromatography electrospray ionization mass spectrometry.

Advanced glycation end-products (AGEs): involvement in aging and in neurodegenerative diseases.

Glyoxal causes inflammatory injury in human vascular endothelial cells.

Rapid analysis of alpha-dicarbonyl compounds by laser desorption/ionization mass spectrometry using 9-(3,4-diaminophenyl)acridine (DAA) as a reactive matrix.

Adverse effects of advanced glycation end products on embryonal development.

The Dicarbonyl Proteome

Suppression of Renal α-Dicarbonyl Compounds Generated following Ureteral Obstruction by Kidney-Specific α-Dicarbonyl/l-Xylulose Reductase

Preparation of Nucleotide Advanced Glycation Endproducts-Imidazopurinone Adducts Formed by Glycation of Deoxyguanosine with Glyoxal and Methylglyoxal

Immunological Detection of N ω -(Carboxymethyl)arginine by a Specific Antibody

Formation of adducts in the reaction of glyoxal with 2'-deoxyguanosine and with calf thymus DNA.

Modification of Vimentin

Three new glycosides from the leaves of Hydrangea macrophylla subsp. serrata (THUNB.) MAKINO.

alpha-Dicarbonyl compounds--key intermediates for the formation of carbohydrate-based melanoidins.

Model Studies on Protein Glycation

Preventing cell death induced by carbonyl stress, oxidative stress or mitochondrial toxins with vitamin B anti-AGE agents.

Different patterns of in vivo pro-oxidant states in a set of cancer- or aging-related genetic diseases.

Rate coefficients for the OH + HC(O)C(O)H (glyoxal) reaction between 210 and 390 K.

Methylglyoxal: its presence and potential scavengers.

The structural modification of DNA nucleosides by nonenzymatic glycation: an in vitro study based on the reactions of glyoxal and methylglyoxal with 2'-deoxyguanosine.

Protein and nucleotide damage by glyoxal and methylglyoxal in physiological systems--role in ageing and disease.