Latest papers

Synthetic and mechanistic pathways of cis and trans-hydroxytamoxifen drug derivatives reacting with Cp*Rh complexes that involve η1-N, η2-N,O, η1-O, and η6 bonding modes, via a novel N-π rearrangement; relative binding affinities and computer docking studies of cis and trans-η6-Cp*Rh-hydroxytamoxifen complexes at the estrogen, ERα and ERβ receptors, and growth inhibition to breast cancer cells.

Novel Helix-Constrained Nociceptin Derivatives Are Potent Agonists and Antagonists of ERK Phosphorylation and Thermal Analgesia in Mice.

Interleukin 1 receptor antagonist is associated with changes in body composition during physiological GH substitution in patients with adult-onset growth hormone deficiency.

Development of prolactin receptor antagonists with reduced pH-dependence of receptor binding.

Large-scale synthesis of 1,1,3,3,6-pentamethyl-1,3-disilaindan-5-ol via a CoBr2/Zn-catalyzed [2+2+2] cycloaddition reaction

Biological diversity from a structurally diverse library: systematically scanning conformational space using a pyranose scaffold.

Effects of 7-O Substitutions on Estrogenic and Anti-Estrogenic Activities of Daidzein Analogues in MCF-7 Breast Cancer Cells.

A second class of nuclear receptors for oxysterols: Regulation of RORα and RORγ activity by 24S-hydroxycholesterol (cerebrosterol)

Isopropylidene substitution increases activity and selectivity of biphenylmethylene 4-pyridine type CYP17 inhibitors.

Expression of Bv8 in Pichia pastoris to identify structural features for receptor binding

Developing drugs to treat osteoporosis: lessons learned?

Synthesis and structure-activity relationships of N3-pyridylpyrazinones as corticotropin-releasing factor-1 (CRF1) receptor antagonists.

Thyromimetics: a review of recent reports and patents (2004 - 2009).

PIN phosphorylation is sufficient to mediate PIN polarity and direct auxin transport.

Genotype and phenotype of patients with gonadotropin-releasing hormone receptor mutations.

The importance of valine 114 in ligand binding in beta(2)-adrenergic receptor.

Low-dose HCG may improve pregnancy rates and lower OHSS in antagonist cycles: a meta-analysis.

Low-dose HCG may improve pregnancy rates and lower OHSS in antagonist cycles: a meta-analysis

Low-dose HCG may improve pregnancy rates and lower OHSS in antagonist cycles: a meta-analysis

Improvement of pharmacological properties of irreversible thyroid receptor coactivator binding inhibitors.