Latest papers

Inhalation of an ethanol-based zileuton formulation provides a reduction of pulmonary adenomas in the A/J mouse model.

[Leg ulcers in patient affected by polycythemia vera in treatment with hydroxycarbamide. Case report].

Hydroxyurea upregulates NKG2D ligand expression in myeloid leukemia cells synergistically with valproic acid and potentially enhances susceptibility of leukemic cells to natural killer cell-mediated cytolysis.

Comparative transcriptome analysis reveals novel roles of the Ras and cyclic AMP signaling pathways in environmental stress response and antifungal drug sensitivity in Cryptococcus neoformans.

[Ru(III)(edta)(H(2)O)](-) mediated oxidation of hydroxyurea with H(2)O(2). Kinetic and mechanistic investigation.

Exposure to hydroxyurea during pregnancy in sickle-beta thalassemia: a report of 2 cases.

No effect of CYP450 and P-glycoprotein on hydroxyurea in vitro metabolism.

The Dbf4-Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4.

Differential expression of a novel gene BRE (TNFRSF1A modulator/BRCC45) in response to stress and biological signals.

Determination of hydroxyurea in serum or plasma using gas chromatography-mass spectrometry (GC-MS).

Dephosphorylation of gamma H2A by Glc7/protein phosphatase 1 promotes recovery from inhibition of DNA replication.

Synthesis, antitumor evaluation and crystal structure of hydroxyurea derivatives.

Activation of the S-phase checkpoint inhibits degradation of the F-box protein Dia2.

Combined effects of arginine and hydroxyurea on BFU-E derived colony growth and HbF synthesis in erythroid progenitors isolated from sickle cell blood.

Chronic subdural hygroma with thrombocythemia: first case report.

Ribonucleotide reductase inhibitors reduce atherosclerosis in a double-injury rabbit model.

Involvement of a chromatin remodeling complex in damage tolerance during DNA replication.

BBAP monoubiquitylates histone H4 at lysine 91 and selectively modulates the DNA damage response.

Stimulated stromal cells induce gamma-globin gene expression in erythroid cells via nitric oxide production.

Exposure to hydroxyurea and pregnancy outcomes in patients with sickle cell anemia.