Latest papers

Synthesis and biological evaluation of novel beta-carbolines as potent cytotoxic and DNA intercalating agents.

Screening by imaging: scaling up single-DNA-molecule analysis with a novel parabolic VA-TIRF reflector and noise-reduction techniques.

Activation of membrane cholesterol by 63 amphipaths.

Millisecond analysis of double stranded DNA with fluorescent intercalator by micro-thermocontrol-device.

Stacking interactions and DNA intercalation.

A single nucleotide polymorphism melt curve assay employing an intercalating dye probe fluorescence resonance energy transfer for forensic analysis

A label-free strategy for SNP detection with high fidelity and sensitivity based on ligation-rolling circle amplification and intercalating of methylene blue.

p21 expression is induced by activation of nuclear nerve growth factor-induced Balpha (Nur77) in pancreatic cancer cells.

The structure-based design, synthesis, and biological evaluation of DNA-binding amide linked bisintercalating bisanthrapyrazole anticancer compounds

ABCG2-mediated DyeCycle Violet efflux defined side population in benign and malignant prostate.

Diffusion-based studies on the self-stacking and nanorod formation of platinum(II) intercalators.

Synthesis, characterization, DNA-binding, and DNA-photocleavage properties of [Co(bpy)2(7-NO2-dppz)]3+, [Co(dmb)2(7-NO2-dppz)]3+, and [Co(phen)2(7-NO2-dppz)]3+ complexes: (7-nitro-dppz = 7-nitro dipyrido[3,2-a:2'-3'-c]phenazine; bpy = 2,2'-bipyridine; dmb = 4,4'-dimethyl-2,2'-bipyridine; phen = 1,10-phenanthroline) and their toxicity on different microorganisms.

Sequence dependent ultrafast electron transfer of nile blue in oligonucleotides.

TioS T-TE--a prototypical thioesterase responsible for cyclodimerization of the quinoline- and quinoxaline-type class of chromodepsipeptides.

DNA binding and oxidative DNA cleavage activity of (mu-oxo)diiron(iii) complexes in visible light.

Binding of [Pt(1C3)(dien)](2+) to the duplex DNA oligonucleotide 5'-d(TGGCCA)-3': the effect of an appended positive charge on the orientation and location of anthraquinone intercalation.

Recognition of abasic sites and single base bulges in DNA by a metalloinsertor.

Selective cytotoxic activity of the marine-derived batzelline compounds against pancreatic cancer cell lines.

A divergent synthesis of minor groove binders with tail group variation.

Optimization of the sequence of twisted intercalating nucleic acids (TINA) forming triple helix with the polypurine tract of the proviral HIV DNA.