Latest papers

Robust TLR4-induced gene expression patterns are not an accurate indicator of human immunity

IRAK1-independent pathways required for the interleukin-1-stimulated activation of the Tpl2 catalytic subunit and its dissociation from ABIN2

CL097, a TLR7/8 ligand, inhibits TLR-4--dependent activation of IRAK-M and BCL-3 expression.

T-lymphocytes: a target for stimulatory and inhibitory effects of zinc ions.

Cloning of IRAK1 and its upregulation in symptomatic mandarin fish infected with ISKNV

Genomic sequence matters: a SNP in microRNA-146a can turn anti-apoptotic.

Common Variation in Genes Related to Innate Immunity and Risk of Adult Glioma

Impaired Priming and Activation of the Neutrophil NADPH Oxidase in Patients with IRAK4 or NEMO Deficiency

IRAK-4 Inhibitors for Inflammation

Adiponectin Promotes Endotoxin Tolerance in Macrophages by Inducing IRAK-M Expression

Differential regulation of Foxp3 and IL-17 expression in CD4 T helper cells by IRAK-1.

[Effect of the liver X receptor agonist on LPS-induced inflammatory response associated factor IRAK-4 and NF-kappaB]

MicroRNAs miR-146a/b negatively modulate the senescence-associated inflammatory mediators IL-6 and IL-8.

Oral tolerance induced by enterobacteria altered the process of lymphocyte recruitment to intestinal microvessels: roles of endothelial cell adhesion molecules, TGF-beta and negative regulators of TLR signaling.

Down-regulation of IRAK-4 is a component of LPS- and CpG DNA-induced tolerance in macrophages.

Immunosuppression associated with interleukin-1R-associated-kinase-M upregulation predicts mortality in Gram-negative sepsis (melioidosis).

Differential gene expression of interleukin-1 receptor associated kinase-1 and interleukin-1 receptor associated kinase-M in peripheral blood mononuclear cells of young and aged rats following preconditioning with endotoxin.

A modeling-derived hypothesis on chronicity in respiratory diseases: desensitized pathogen recognition secondary to hyperactive IRAK/TRAF6 signaling.

Involvement of interleukin-1 receptor-associated kinase (IRAK)-M in toll-like receptor (TLR) 7-mediated tolerance in RAW 264.7 macrophage-like cells.

MyD88 and TRIF mediate the cyclic adenosine monophosphate (cAMP) induced corticotropin releasing hormone (CRH) expression in JEG3 choriocarcinoma cell line.