Latest papers

Interdependence of receptor activation and ligand binding in HCN2 pacemaker channels.

C terminus of nucleotide binding domain 1 contains critical features for cystic fibrosis transmembrane conductance regulator trafficking and activation.

Leu85 in the beta1-beta2 linker of ASIC1 slows activation and decreases the apparent proton affinity by stabilizing a closed conformation.

Alpha-conotoxin AuIB isomers exhibit distinct inhibitory mechanisms and differential sensitivity to stoichiometry of alpha3beta4 nicotinic acetylcholine receptors.

O-mycoloylated proteins from Corynebacterium: an unprecedented post-translational modification in bacteria.

Biochemistry. Old gate gets a new look.

Structure of the human BK channel Ca2+-activation apparatus at 3.0 A resolution.

Structural basis for the coupling between activation and inactivation gates in K(+) channels.

Structural mechanism of C-type inactivation in K(+) channels.

Calcium window currents, periodic forcing, and chaos: understanding single neuron response with a discontinuous one-dimensional map.

Fragile X mental retardation protein controls gating of the sodium-activated potassium channel Slack.

Two residues in the extracellular domain convert a nonfunctional ASIC1 into a proton-activated channel.

Potassium secretion by voltage-gated potassium channel Kv1.3 in the rat kidney.

Ceramide modulates HERG potassium channel gating by translocation into lipid rafts.

Upregulation of store-operated Ca2+ entry in dystrophic mdx mouse muscle.

Lubiprostone reverses the inhibitory action of morphine on intestinal secretion in guinea pig and mouse.

Endothelium-derived nitric oxide inhibits the relaxation of the porcine coronary artery to natriuretic peptides by desensitizing big conductance calcium-activated potassium channels of vascular smooth muscle.

The two C-terminal tyrosines stabilize occluded Na/K pump conformations containing Na or K ions.

Function of the HVCN1 proton channel in airway epithelia and a naturally occurring mutation, M91T.

Frequency and release flux of calcium sparks in rat cardiac myocytes: a relation to RYR gating.