Latest papers

Stereochemistry of eudesmane cation formation during catalysis by aristolochene synthase from Penicillium roqueforti.

X-ray crystallographic studies of substrate binding to aristolochene synthase suggest a metal ion binding sequence for catalysis.

Substrate specificity of platypus venom L-to-D-peptide isomerase.

CYP725A4 from yew catalyzes complex structural rearrangement of taxa-4(5),11(12)-diene into the cyclic ether 5(12)-oxa-3(11)-cyclotaxane.

Study of anoxic and oxic cholesterol metabolism by Sterolibacterium denitrificans.

[Peroxisomal D-bifunctional enzyme deficiency. A case report].

A single residue switch converts abietadiene synthase into a pimaradiene specific cyclase.

Quantum chemical modeling of enzymatic reactions: the case of 4-oxalocrotonate tautomerase.

Synthetic efficiency in enzyme mechanisms involving carbocations: aristolochene synthase.

Probing the reaction mechanism of aristolochene synthase with 12,13-difluorofarnesyl diphosphate.

Isolation and characterization of unsaturated fatty acid auxotrophs of Streptococcus pneumoniae and Streptococcus mutans.

Sequential quadratic programming method for determining the minimum energy path.

Competitive inhibition of aristolochene synthase by phenyl-substituted farnesyl diphosphates: evidence of active site plasticity.

Kinetic and stereochemical analysis of YwhB, a 4-oxalocrotonate tautomerase homologue in Bacillus subtilis: mechanistic implications for the YwhB- and 4-oxalocrotonate tautomerase-catalyzed reactions.

Aristolochene synthase-catalyzed cyclization of 2-fluorofarnesyl-diphosphate to 2-fluorogermacrene A.

The crystal and solution studies of glucosamine-6-phosphate synthase from Candida albicans.

The pesticide adjuvant, Toximul, alters hepatic metabolism through effects on downstream targets of PPARalpha.

Heterologous expression of linoleic acid isomerase from Propionibacterium acnes and anti-proliferative activity of recombinant trans-10, cis-12 conjugated linoleic acid.

Substrate orientation in 4-oxalocrotonate tautomerase and its effect on QM/MM energy profiles.

The x-ray structure of dTDP-4-keto-6-deoxy-D-glucose-3,4-ketoisomerase.