Latest papers

Attention-deficit hyperactivity disorder (ADHD) and glial integrity: S100B, cytokines and kynurenine metabolism--effects of medication.

Interferon-γ-Responsive Nonhematopoietic Cells Regulate the Immune Response to Mycobacterium tuberculosis

Shifting the balance of brain tryptophan metabolism elicited by isolation housing and systemic administration of lipopolysaccharide in mice

Increased plasma kynurenine values and kynurenine-tryptophan ratios after major trauma are early indicators for the development of sepsis.

Hypercoagulability is independently associated with kynurenine pathway activation in dialysed uraemic patients.

5-Hydroxyanthranilic acid, a tryptophan metabolite, generates oxidative stress and neuronal death via p38 activation in cultured cerebellar granule neurones.

Tryptophan degradation in multiple trauma patients: survivors compared with non-survivors.

On the relationship between the two branches of the kynurenine pathway in the rat brain in vivo.

Alteration of kynurenic acid concentration in rat plasma following optically pure kynurenine administration: a comparative study between enantiomers.

Indoleamine 2,3-dioxygenase attenuates inhibitor development in gene-therapy-treated hemophilia A mice

Recent advances in the treatment of amyotrophic lateral sclerosis. Emphasis on kynurenine pathway inhibitors.

Age and circadian influences on picolinic acid concentrations in human cerebrospinal fluid.

Differential regulation of indoleamine-2,3-dioxygenase (IDO) by HIV type 1 clade B and C Tat protein.

New promises for manipulation of kynurenine pathway in cancer and neurological diseases.

Anti-infectious activity of tryptophan metabolites in the L-tryptophan-L-kynurenine pathway.

[Tryptophan and its metabolites in renal allograft recipients].

The evolution of schizophrenia: a model for selection by infection, with a focus on NAD.

Immune system modulation in patients with malignant and benign breast disorders: tryptophan degradation and serum neopterin.

Function of the tryptophan metabolite, L-kynurenine, in human corneal endothelial cells.

Tryptophan and kynurenine levels in lenses of Wistar and accelerated-senescence OXYS rats.