Latest papers

Total synthesis of the alpha-glucosidase inhibitors schulzeine A, B, and C and a structural revision of schulzeine A.

Ribosomal synthesis of peptides with C-terminal lactams, thiolactones, and alkylamides.

High yield synthesis of 12-aminolauric acid by "enzymatic transcrystallization" of omega-laurolactam using omega-laurolactam hydrolase from Acidovorax sp. T31.

Synthesis, binding affinity and SAR of new benzolactam derivatives as dopamine D3 receptor ligands.

Spectral properties of self-assembled squaraine-tetralactam: a theoretical assessment.

Caulerpenyne binding to tubulin: structural modifications by a non conventional pharmacological agent.

Stereoselective plasma protein binding and target tissue distribution of clausenamide enantiomers in rats.

Effect of cobalt and vitamin B12 on the production of salinosporamides by Salinispora tropica.

Ring-opening reaction of Bus- and SES-protected aziridines using lithiated dithianes.

Synthesis, ex vivo and in vitro hydrolysis study of an indoline derivative designed as an anti-inflammatory with reduced gastric ulceration properties.

A catalytically and genetically optimized beta-lactamase-matrix based assay for sensitive, specific, and higher throughput analysis of native henipavirus entry characteristics.

Natural product glycosyltransferases: properties and applications.

Modulation of sodium channel inactivation gating by a novel lactam: implications for seizure suppression in chronic limbic epilepsy.

Thieno[3,2-e]diazepinediones and 3-thienylimidazolidinediones syntheses: regio-controlled ring opening of thiaisatoic anhydride by alpha-amino acids.

Cyclic ketimines as superior electrophiles for NHC-catalyzed homoenolate additions with broad scope and low catalyst loadings.

Synthesis of highly substituted pyroglutamates via a domino Michael addition-Claisen rearrangement-lactamisation approach.

Leaving groups prolong the duration of 20S proteasome inhibition and enhance the potency of salinosporamides.

Fast, acid-free, and selective lactamization of lactones in ionic liquids.

Thermal elimination of diethyldithiocarbamates and application in the synthesis of (+/-)-ferrugine.

Cyclic imine nitro-Mannich/lactamization cascades: a direct stereoselective synthesis of multicyclic piperidinone derivatives.