Latest papers

Stimulus-dependent regulation of the phagocyte NADPH oxidase by a VAV1, Rac1, and PAK1 signaling axis.

Suppression of the invasive capacity of rat ascites hepatoma cells by knockdown of Slingshot or LIM kinase.

Dual regulation of cofilin activity by LIM kinase and Slingshot-1L phosphatase controls platelet-derived growth factor-induced migration of human aortic smooth muscle cells.

LIM kinase-mediated cofilin phosphorylation during mitosis is required for precise spindle positioning.

Annexin A2 phosphorylation mediates cell scattering and branching morphogenesis via cofilin Activation.

B-RAF regulation of Rnd3 participates in actin cytoskeletal and focal adhesion organization.

Downregulation of LIM kinase 1 suppresses ocular inflammation and fibrosis.

Identification and characterization of RHOA-interacting proteins in bovine spermatozoa.

A role for S1P signalling in axon guidance in the Xenopus visual system.

The LIM-only protein FHL2 mediates ras-induced transformation through cyclin D1 and p53 pathways.

Williams syndrome

The phosphorylation of p25/TPPP by LIM kinase 1 inhibits its ability to assemble microtubules.

Phosphorylated LIM kinases colocalize with gamma-tubulin in centrosomes during early stages of mitosis.

Functional protein kinase arrays reveal inhibition of p-21-activated kinase 4 by alpha-synuclein oligomers.

Cofilin activity downstream of Pak1 regulates cell protrusion efficiency by organizing lamellipodium and lamella actin networks.

Direct stimulation of receptor-controlled phospholipase D1 by phospho-cofilin.

Genetic contributions to white matter architecture revealed by diffusion tensor imaging in Williams syndrome.

Parkin interacts with LIM Kinase 1 and reduces its cofilin-phosphorylation activity via ubiquitination

Drosophila T-box transcription factor Optomotor-blind prevents pathological folding and local overgrowth in wing epithelium through confining Hh signal

Beta-arrestin-dependent regulation of the cofilin pathway downstream of protease-activated receptor-2.