Latest papers

Striatal microRNA controls cocaine intake through CREB signalling.

Increased circulating cell signalling phosphoproteins in sera are useful for the detection of pancreatic cancer.

Expression of MAP3 kinase COT1 is up-regulated by 1,25-dihydroxyvitamin D3 in parallel with activated c-jun during differentiation of human myeloid leukemia cells.

14-3-3 epsilon dynamically interacts with key components of mitogen-activated protein kinase signal module for selective modulation of the TNF-alpha-induced time course-dependent NF-kappaB activity.

Regulation of (pro)renin receptor expression by glucose-induced mitogen-activated protein kinase, nuclear factor-kappaB, and activator protein-1 signaling pathways.

LMP1 regulates periodontal ligament progenitor cell proliferation and differentiation.

Icariin attenuates lipopolysaccharide-induced microglial activation and resultant death of neurons by inhibiting TAK1/IKK/NF-kappaB and JNK/p38 MAPK pathways.

TAK1 Suppresses a NEMO-Dependent but NF-κB-Independent Pathway to Liver Cancer

c-Jun-NH2 terminal kinase (JNK)-mediates AP-1 activation by thioredoxin: phosphorylation of cJun, JunB, and Fra-1.

TAK1 mediates BMP signaling in cartilage.

The phosphatase Shp2 is required for signaling by the Kaposi's sarcoma-associated herpesvirus viral GPCR in primary endothelial cells

A receptor-independent, cell-based JAK activation assay for screening for JAK3-specific inhibitors

Tpl2/AP-1 enhances murine gammaherpesvirus 68 lytic replication.

Caspase-mediated cleavage, IAP binding, and ubiquitination: linking three mechanisms crucial for Drosophila NF-kappaB signaling.

Nuclear function of Smad7 promotes myogenesis.

Impact of feedback phosphorylation and Raf heterodimerization on normal and mutant B-Raf signaling.

Inhibition of tumor progression locus 2 protein kinase decreases lipopolysaccharide-induced tumor necrosis factor alpha production due to the inhibition of the tip-associated protein induction in RAW264.7 cells.

Inhibition of tumor progression locus 2 protein kinase suppresses receptor activator of nuclear factor-kappaB ligand-induced osteoclastogenesis through down-regulation of the c-Fos and nuclear factor of activated T cells c1 genes.

Decreased expression of glutaredoxin 1 is required for transforming growth factor-β1-mediated epithelial–mesenchymal transition of EpRas mammary epithelial cells

Activation of the alpha3 integrin affects TRAF6 function in the IL-1 signaling pathway of CACO-2 epithelial cells.