Latest papers

Stage-specific inhibitory effects and associated mechanisms of silibinin on tumor progression and metastasis in transgenic adenocarcinoma of the mouse prostate model.

Clinical assessment of CYP2D6-mediated herb-drug interactions in humans: effects of milk thistle, black cohosh, goldenseal, kava kava, St. John's wort, and Echinacea.

Milk thistle extracts inhibit the oxidation of low-density lipoprotein (LDL) and subsequent scavenger receptor-dependent monocyte adhesion.

Effects of carvacrol on defects of ischemia-reperfusion in the rat liver.

Pretreatment of milk thistle seed to increase the silymarin yield: an alternative to petroleum ether defatting.

Silymarin, the Antioxidant Component of Silybum marianum, Prevents Sepsis-Induced Acute Lung and Brain Injury

Protective and therapeutic effects of an extract mixture of alder tree, labiate herb, milk thistle green bean-rice bran fermentation, and turnip against ethanol-induced toxicity in the rat.

Antioxidant and mitochondrial protective effects of silibinin in cold preservation-warm reperfusion liver injury.

Exacerbation of hemochromatosis by ingestion of milk thistle.

What's in a name?

In vitro evaluation and pharmacokinetics in dogs of solid dispersion pellets containing Silybum marianum extract prepared by fluid-bed coating.

Pharmacokinetics and metabolic profile of free, conjugated, and total silymarin flavonolignans in human plasma after oral administration of milk thistle extract.

Screening for soil streptomycetes from North Jordan that can produce herbicidal compounds.

Flavonolignans from Silybum marianum moderate UVA-induced oxidative damage to HaCaT keratinocytes.

Silymarin, the antioxidant component of Silybum marianum, protects against burn-induced oxidative skin injury.

Gram-scale purification of flavonolignan diastereoisomers from Silybum marianum (Milk Thistle) extract in support of preclinical in vivo studies for prostate cancer chemoprevention.

Effect of silymarin and vitamin E on gentamicin-induced nephrotoxicity in dogs.

p21 and p27 induction by silibinin is essential for its cell cycle arrest effect in prostate carcinoma cells.

Genetic properties of milk thistle ecotypes from Iran for morphological and flavonolignans characters.

Silymarin prevents palmitate-induced lipotoxicity in HepG2 cells: involvement of maintenance of Akt kinase activation.