Latest papers

Epidermal growth factor receptor and protein kinase C signaling to ERK2: spatiotemporal regulation of ERK2 by dual specificity phosphatases.

A cell-active inhibitor of mitogen-activated protein kinase phosphatases restores paclitaxel-induced apoptosis in dexamethasone-protected cancer cells.

In vitro translation with [34S]-labeled methionine, selenomethionine, and telluromethionine.

Role of mitogen-activated protein kinase phosphatases (MKPs) in cancer.

Microtubule disruption and tumor suppression by mitogen-activated protein kinase phosphatase 4.

Epidermal terminal differentiation depends on B lymphocyte-induced maturation protein-1.

DUSP22/LMW-DSP2 regulates estrogen receptor-alpha-mediated signaling through dephosphorylation of Ser-118.

A molecular link between E2F-1 and the MAPK cascade.

Chemopreventive anti-inflammatory activities of curcumin and other phytochemicals mediated by MAP kinase phosphatase-5 in prostate cells.

HoxA10 activates transcription of the gene encoding mitogen-activated protein kinase phosphatase 2 (Mkp2) in myeloid cells.

Novel function of DUSP14/MKP6 (dual specific phosphatase 14) as a nonspecific regulatory molecule for delayed-type hypersensitivity.

Crystal structure of the MAP kinase binding domain and the catalytic domain of human MKP5.

Quinoxalinylurea derivatives as a novel class of JSP-1 inhibitors.

Modulation of replicative senescence of diploid human cells by nuclear ERK signaling.

Crystal structure of human dual specificity phosphatase, JNK stimulatory phosphatase-1, at 1.5 A resolution.

Mapping ERK2-MKP3 binding interfaces by hydrogen/deuterium exchange mass spectrometry.

Inhibition of gluconeogenesis through transcriptional activation of EGR1 and DUSP4 by AMP-activated kinase.

Active ERK contributes to protein translation by preventing JNK-dependent inhibition of protein phosphatase 1.

Crystal Structure of the Catalytic Domain of Human MAP Kinase Phosphatase 5: Structural Insight into Constitutively Active Phosphatase

Mitogen-activated protein kinase phosphatase 2: a novel transcription target of p53 in apoptosis.