Latest papers

Adenylylation control by intra- or intermolecular active-site obstruction in Fic proteins.

Probing structural features of Alzheimer's amyloid-β pores in bilayers using site-specific amino acid substitutions.

Post-translational modification of Cu/Zn superoxide dismutase under anaerobic conditions.

Structural and biophysical insights into the ligand-free Pitx2 homeodomain and a ring dermoid of the cornea inducing homeodomain mutant.

Structure, dynamics, and antimicrobial and immune modulatory activities of human LL-23 and its single-residue variants mutated on the basis of homologous primate cathelicidins.

Nanomechanical recognition of sphingomyelin-rich membrane domains by atomic force microscopy.

Cell-Type-Based Analysis of MicroRNA Profiles in the Mouse Brain

Single-molecule studies reveal the function of a third polymerase in the replisome.

Ester-linked hen egg white lysozyme shows a compact fold in a molecular dynamics simulation - possible causes and sensitivity of experimentally observable quantities to structural changes maintaining this compact fold.

Structural basis of pre-let-7 miRNA recognition by the zinc knuckles of pluripotency factor Lin28.

A metal switch for controlling the activity of molecular motor proteins.

Mechanism of mismatch recognition revealed by human MutSβ bound to unpaired DNA loops.

Reconstructing human exposures using biomarkers and other "clues".

Ndc10 is a platform for inner kinetochore assembly in budding yeast.

Three-component reaction discovery enabled by mass spectrometry of self-assembled monolayers.

Small-molecule conversion of toxic oligomers to nontoxic β-sheet-rich amyloid fibrils.

A synthetic molecular pentafoil knot.

An ankyrin-repeat ubiquitin-binding domain determines TRABID's specificity for atypical ubiquitin chains.

Mechanism of mismatch recognition revealed by human MutSβ bound to unpaired DNA loops.

The guanine cap of human guanylate-binding protein 1 is responsible for dimerization and self-activation of GTP hydrolysis.