Latest papers

Tel1(ATM) and Rad3(ATR) phosphorylate the telomere protein Ccq1 to recruit telomerase and elongate telomeres in fission yeast.

Interpretation of genotypic resistance to predict darunavir/ritonavir failure in antiretroviral experienced patients.

Chronic myeloid leukemia: clinical impact of BCR-ABL1 mutations and other lesions associated with disease progression.

Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities.

Hereditary ovarian cancer: beyond the usual suspects.

The Gal3p transducer of the GAL regulon interacts with the Gal80p repressor in its ligand-induced closed conformation.

Neonatal screening for lysosomal storage disorders: feasibility and incidence from a nationwide study in Austria.

RAS mutations in cutaneous squamous-cell carcinomas in patients treated with BRAF inhibitors.

Structural and biophysical insights into the ligand-free Pitx2 homeodomain and a ring dermoid of the cornea inducing homeodomain mutant.

Lessons learned from 20 years of newborn screening for cystic fibrosis.

Structure, dynamics, and antimicrobial and immune modulatory activities of human LL-23 and its single-residue variants mutated on the basis of homologous primate cathelicidins.

RAF around the edges--the paradox of BRAF inhibitors.

R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants.

PRRT2 Mutations Cause Benign Familial Infantile Epilepsy and Infantile Convulsions with Choreoathetosis Syndrome

Phosphorylation of the p68 subunit of Pol δ acts as a molecular switch to regulate its interaction with PCNA.

NMDA Receptor-Mediated PIP5K Activation to Produce PI(4,5)P2 Is Essential for AMPA Receptor Endocytosis during LTD

Otic Mesenchyme Cells Regulate Spiral Ganglion Axon Fasciculation through a Pou3f4/EphA4 Signaling Pathway

Histone Deacetylase 5 Limits Cocaine Reward through cAMP-Induced Nuclear Import

Integrins regulate repulsion-mediated dendritic patterning of drosophila sensory neurons by restricting dendrites in a 2D space.

Vti1a Identifies a Vesicle Pool that Preferentially Recycles at Rest and Maintains Spontaneous Neurotransmission