Latest papers

Absorption, distribution, excretion, and pharmacokinetics of 14C-pyronaridine tetraphosphate in male and female Sprague-Dawley rats.

[Gemifloxacin for the treatment of uncomplicated urinary infections (acute cystitis)]

AAA-DDD triple hydrogen bond complexes.

Discovery of a Novel Series of Quinolone and Naphthyridine Derivatives as Potential Topoisomerase I Inhibitors by Scaffold Modification

One-Pot Synthesis of 4,5-Biphenyl-2-pyrimidinylguanidine Derivatives

Diversity Synthesis of Pyrimido[4,5- b ][1,6]naphthyridine and Its Derivatives under Microwave Irradiation

Acute modulation of myocardial function by angiotensin 1-7.

An in vivo chemical library screen in Xenopus tadpoles reveals novel pathways involved in angiogenesis and lymphangiogenesis.

1,8-Naphthyridine-3-carboxamide derivatives with anticancer and anti-inflammatory activity.

Synthesis and in-vitro antitumour activity of new naphthyridine derivatives on human pancreatic cancer cells.

Trovafloxacin enhances the inflammatory response to a Gram-negative or a Gram-positive bacterial stimulus, resulting in neutrophil-dependent liver injury in mice.

The role of the hemostatic system in murine liver injury induced by coexposure to lipopolysaccharide and trovafloxacin, a drug with idiosyncratic liability.

The use of oxadiazole and triazole substituted naphthyridines as HIV-1 integrase inhibitors. Part 1: Establishing the pharmacophore.

1,3,4-Oxadiazole substituted naphthyridines as HIV-1 integrase inhibitors. Part 2: SAR of the C5 position.

Protective Effect of 4-Methoxy-5-hydroxycanthin-6-one, A Natural Alkaloid, on Dextran Sulfate Sodium-Induced Rat Colitis

Allosteric inhibitors of Akt1 and Akt2: discovery of [1,2,4]triazolo[3,4-f][1,6]naphthyridines with potent and balanced activity.

Unnatural imidazopyridopyrimidine:naphthyridine base pairs: selective incorporation and extension reaction by DNA polymerases.

New hexahydrodiazocino-naphthyridine triones as HIV-1 integrase inhibitors: WO2008048538 A1.

[Study of efficacy of modern fluoroquinolones against agent of glanders in experiments in vivo]

Corneal deposits after topical tosufloxacin in a patient with poor tear secretion.