Latest papers

Androgen receptor-mTOR crosstalk is regulated by testosterone availability: implication for prostate cancer cell survival.

Defining hypotension in moderate to severely injured trauma patients: raising the bar for the elderly.

Platinum-catalyzed cross-dehydrogenative coupling reaction in the absence of oxidant.

Switching from (R)- to (S)-selective chemoenzymatic DKR of amines involving sulfanyl radical-mediated racemization.

Direct oxidative coupling of benzenes with acrylonitriles to cinnamonitriles catalyzed by Pd(OAc)(2)/HPMoV/O(2) system.

Benzoyl radicals from (hetero)aromatic aldehydes. Decatungstate photocatalyzed synthesis of substituted aromatic ketones.

A facile method for the synthesis of oxindole based quaternary alpha-aminonitriles via the Strecker reaction.

Design, synthesis, characterisation and chemical reactivity of mixed-ligand platinum(II) oxadiazoline complexes with potential cytotoxic properties.

PTEN sensitizes MDA-MB-468 cells to inhibition of MEK/Erk signaling for the blockade of cell proliferation.

Efficacy of maximal androgen blockade versus castration alone in the treatment of advanced prostate cancer: a retrospective clinical experience from a Chinese medical centre.

Efficacy and tolerability of vildagliptin as an add-on to glimepiride in Japanese patients with Type 2 diabetes mellitus.

Down-regulation of heat-shock protein 70 (HSP-70) correlated with responsiveness to neoadjuvant aromatase inhibitor therapy in breast cancer patients.

Combination therapy with nateglinide and vildagliptin improves postprandial metabolic derangements in Zucker fatty rats.

Towards molecular diversity: dealkylation of tert-butyl amine in Ugi-type multicomponent reaction product establishes tert-butyl isocyanide as a useful convertible isonitrile.

Ultrafast reversible ligand isomerisation in Na2[Fe(CN)5NO] x 2 H2O single crystals.

Salutary effects of 17beta-estradiol on Peyer's patch T cell functions following trauma-hemorrhage.

AT-101 (R-(-)-gossypol acetic acid) enhances the effectiveness of androgen deprivation therapy in the VCaP prostate cancer model.

Ganglioside GD1a suppression of NOS2 expression via ERK1 pathway in mouse osteosarcoma FBJ cells.

Pesticide residues in dried table grapes from the Aegean region of Turkey.

McCune-Albright syndrome (MAS): early and extensive bone fibrous dysplasia involvement and mistaken identity oophorectomy.