Latest papers

Expression and characterization of the TNT nitroreductase of Pseudomonas sp. HK-6 in Escherichia coli.

A mechanism for cross-resistance to nifurtimox and benznidazole in trypanosomes.

Crystal structure of a minimal nitroreductase, ydjA, from Escherichia coli K12 with and without FMN cofactor.

Escherichia coli nitroreductase plus CB1954 enhances the effect of radiotherapy in vitro and in vivo.

Combining gene and immunotherapy for prostate cancer.

Characterization of the CopR regulon of Lactococcus lactis IL1403.

The nitroreductase prodrug SN 28343 enhances the potency of systemically administered armed oncolytic adenovirus ONYX-411(NTR).

Crystallization and preliminary X-ray diffraction analysis of ydjA, a minimal nitroreductase from Escherichia coli K12.

Identification and characterization of the flavin:NADH reductase (PrnF) involved in a novel two-component arylamine oxygenase.

Early nifurtimox-induced biochemical and ultrastructural alterations in rat heart.

Azoreductase from Rhodobacter sphaeroides AS1.1737 is a flavodoxin that also functions as nitroreductase and flavin mononucleotide reductase.

Crystallization and preliminary X-ray characterization of the Bacillus amyloliquefaciens YwrO enzyme.

TNT biotransformation: when chemistry confronts mineralization.

Chloramphenicol is a substrate for a novel nitroreductase pathway in Haemophilus influenzae.

Nifurtimox nitroreductase activity in different cellular fractions from male rat pancreas. Biochemical and ultrastructural alterations.

The orientationally controlled assembly of genetically modified enzymes in an amperometric biosensor.

A novel Giardia lamblia nitroreductase, GlNR1, interacts with nitazoxanide and other thiazolides.

Validation of nitroreductase, a prodrug-activating enzyme, mediated cell death in embryonic zebrafish (Danio rerio).

Characterization of a pseudomonad 2-nitrobenzoate nitroreductase and its catabolic pathway-associated 2-hydroxylaminobenzoate mutase and a chemoreceptor involved in 2-nitrobenzoate chemotaxis.

Ablation of central nervous system progenitor cells in transgenic rats using bacterial nitroreductase system.