Latest papers

The significance of putative urinary markers of illicit heroin use after consumption of poppy seed products.

Development of a novel nitro-derivative of noscapine for the potential treatment of drug-resistant ovarian cancer and T-cell lymphoma.

Noscapine and diltiazem augment taxol and radiation-induced S-phase arrest and clonogenic death of C6 glioma in vitro.

Noscapine inhibits hypoxia-mediated HIF-1alpha expression andangiogenesis in vitro: a novel function for an old drug.

Rational design of the microtubule-targeting anti-breast cancer drug EM015.

Anxiolytic effect of noscapine in mice.

Atmospheric pressure ionisation mass spectrometric fragmentation pathways of noscapine and papaverine revealed by multistage mass spectrometry and in-source deuterium labelling.

Identification of novel and improved antimitotic agents derived from noscapine.

[Analysis of two year heroin seizures in the Liege area]

Principal opium alkaloids as possible biochemical markers for the source identification of Indian opium.

Noscapine suppresses angiotensin converting enzyme inhibitors-induced cough.

Synthesis and radioligand binding studies of C-5- and C-8-substituted 1-(3,4-dimethoxybenzyl)-2,2-dimethyl-1,2,3,4-tetrahydroisoquinoliniums as SK channel blockers related to N-methyl-laudanosine and N-methyl-noscapine.

Simultaneous determination of methylephedrine and noscapine in human plasma by liquid chromatography-tandem mass spectrometry.

Discovery of S-phase arresting agents derived from noscapine.

Thin-layer chromatography-densitometry and liquid chromatography analysis of alkaloids in leaves of Papaver somniferum under stress conditions.

Targeting microtubules for cancer chemotherapy.

Development and validation of a capillary electrophoresis method for the determination of codeine, diphenhydramine, ephedrine and noscapine in pharmaceuticals

Electrophysiological characterization of the SK channel blockers methyl-laudanosine and methyl-noscapine in cell lines and rat brain slices.

Noscapine crosses the blood-brain barrier and inhibits glioblastoma growth.

Modulatory influence of noscapine on the ethanol-altered hepatic biotransformation system enzymes, glutathione content and lipid peroxidation in vivo in rats.