Latest papers

Structure-activity relationships of 2',5'-oligoadenylate analogue modifications of prostate-specific membrane antigen (PSMA) antagonists.

Genotyping of -374A/T, -429A/G, and 63 bp Ins/del polymorphisms of rage by rapid one-step hexaprimer amplification refractory mutation system polymerase chain reaction in breast cancer patients.

Synthesis of C3' Modified Nucleosides for Selective Generation of the C3'-Deoxy-3'-thymidinyl Radical: A Proposed Intermediate in LEE Induced DNA Damage.

Dissecting Chemical Interactions Governing RNA Polymerase II Transcriptional Fidelity.

Elements of Nucleotide Specificity in the Trypanosoma brucei Mitochondrial RNA Editing Enzyme RET2.

Synthesis and Pairing Properties of Oligodeoxynucleotides Containing Bicyclo-RNA and Bicyclo-ANA Modifications.

Shrimp oncoprotein nm23 is a functional nucleoside diphosphate kinase.

Progress in the development of anti-hepatitis C virus nucleoside and nucleotide prodrugs.

Structures of KlenTaq DNA Polymerase Caught While Incorporating C5-Modified Pyrimidine and C7-Modified 7-Deazapurine Nucleoside Triphosphates.

Synthesis and biological properties of chemically modified siRNAs bearing 1-deoxy-d-ribofuranose in their 3′-overhang region

Virological response to entecavir is associated with a better clinical outcome in chronic hepatitis B patients with cirrhosis.

Ten paths to the discovery of antivirally active nucleoside and nucleotide analogues.

Convenient and efficient syntheses of oligodeoxyribonucleotides containing o (6)-(carboxymethyl)guanine and o (6)-(4-oxo-4-(3-pyridyl)butyl)guanine.

Design, synthesis, antiviral, and cytotoxic evaluation of novel phosphonylated 1,2,3-triazoles as acyclic nucleotide analogues.

A 2'-Deoxy-2'-Fluoro-2'-C-Methyl Uridine Cyclopentyl Carbocyclic Analog and Its Phosphoramidate Prodrug as Inhibitors of HCV NS5B Polymerase.

Modified Synthesis of 3'-OTBDPS-Protected Furanoid Glycal.

Synthesis and biological evaluation of (3's)-3'-deoxy-3'-fluoro-3'-C-ethynylcytidine.

Analysis of Human DNA-Arginine Photoadduct Modified with Peroxynitrite.

Effect of lovastatin therapy and withdrawal on serum uric Acid level in people with type 2 diabetic nephropathy.

Synthesis, molecular conformation and activity against herpes simplex virus of (e)-5-(2-bromovinyl)-2'-deoxycytidine analogs.