Latest papers

Focal adhesion kinase is essential for cardiac looping and multichamber heart formation.

PRO-051, an antisense oligonucleotide for the potential treatment of Duchenne muscular dystrophy.

Native mRNA antisense-accessible sites library for the selection of antisense oligonucleotides, PNAs, and siRNAs.

Antisense antibiotics: a brief review of novel target discovery and delivery.

Effect of the abrogation of TGF-beta1 by antisense oligonucleotides on the expression of TGF-beta-isoforms and their receptors I and II in isolated fibroblasts from keloid scars.

C-reactive protein-mediated vascular injury requires complement.

An antisense microwalk reveals critical role of an intronic position linked to a unique long-distance interaction in pre-mRNA splicing.

Extracellular 3',5'-cAMP-adenosine pathway inhibits glomerular mesangial cell growth.

Growth inhibition of SK-MEL-30 human melanoma cells by antisense c-myc oligonucleotides delivered by poly(N-isopropylacrylamide)/ poly(ethyleneimine) copolymer.

Specific down regulation of 3T3-L1 adipocyte differentiation by cell-permeable antisense HIF1alpha-oligonucleotide.

Efficient delivery of intact phosphodiester oligonucleotides by poly-beta-amino esters.

The development of antisense oligonucleotide therapies for Duchenne muscular dystrophy: report on a TREAT-NMD workshop hosted by the European Medicines Agency (EMA), on September 25th 2009.

Effect of Tbx1 knock-down on cardiac performance in zebrafish.

Gemcitabine sensitivity can be induced in pancreatic cancer cells through modulation of miR-200 and miR-21 expression by curcumin or its analogue CDF.

The alkyl-connected 2-amino-6-vinylpurine (AVP) crosslinking agent for improved selectivity to the cytosine base in RNA

Exonic sequences provide better targets for antisense oligonucleotides than splice site sequences in the modulation of Duchenne muscular dystrophy splicing.

Stepwise synthesis of oligonucleotide–peptide conjugates containing guanidinium and lipophilic groups in their 3′-termini

Auger-mediated cytotoxicity of cancer cells in culture by an 125I-antisense oligomer delivered as a three-component streptavidin nanoparticle.

Antisense oligonucleotide against miR-21 inhibits migration and induces apoptosis in leukemic K562 cells.

The biological effect of an antisense oligonucleotide depends on its route of endocytosis and trafficking.