Latest papers

Spermine Metabolism and Anticancer Therapy

Comprehensive computational analysis of Hmd enzymes and paralogs in methanogenic Archaea.

Correction of pre-steady-state KIEs for isotopic impurities and the consequences of kinetic isotope fractionation.

No association of single nucleotide polymorphisms in one-carbon metabolism genes with prostate cancer risk.

The enzyme aromatic amine dehydrogenase induces a substrate conformation crucial for promoting vibration that significantly reduces the effective potential energy barrier to proton transfer.

Driving force analysis of proton tunnelling across a reactivity series for an enzyme-substrate complex.

ADP competes with FAD binding in putrescine oxidase.

In vitro and in vivo inhibition of plant polyamine oxidase activity by polyamine analogues.

A putative peroxisomal polyamine oxidase, AtPAO4, is involved in polyamine catabolism in Arabidopsis thaliana.

Niemann-Pick C1 functions in regulating lysosomal amine content.

Expression, purification, crystallization and preliminary X-ray studies of histamine dehydrogenase from Nocardioides simplex.

The iron-sulfur cluster of electron transfer flavoprotein-ubiquinone oxidoreductase is the electron acceptor for electron transfer flavoprotein.

Apoplastic polyamine oxidation plays different roles in local responses of tobacco to infection by the necrotrophic fungus Sclerotinia sclerotiorum and the biotrophic bacterium Pseudomonas viridiflava.

Bridging the gap between plant and mammalian polyamine catabolism: a novel peroxisomal polyamine oxidase responsible for a full back-conversion pathway in Arabidopsis.

Polyamine catabolism in colorectal cancer cells following treatment with oxaliplatin, 5-fluorouracil and N1, N11 diethylnorspermine.

Characterization of a Helicobacter hepaticus putA mutant strain in host colonization and oxidative stress.

Roles of coenzyme F420-reducing hydrogenases and hydrogen- and F420-dependent methylenetetrahydromethanopterin dehydrogenases in reduction of F420 and production of hydrogen during methanogenesis.

The novel polyamine analogue CGC-11093 enhances the antimyeloma activity of bortezomib.

Spermidine exodus and oxidation in the apoplast induced by abiotic stress is responsible for H2O2 signatures that direct tolerance responses in tobacco.

Increased spermine oxidase expression in human prostate cancer and prostatic intraepithelial neoplasia tissues.