Latest papers

Relationship between nuclear sequestration of PLCzeta and termination of PLCzeta-induced Ca2+ oscillations in mouse eggs.

General and versatile autoinhibition of PLC isozymes.

Role and mechanism of phosphatidylinositol-specific phospholipase C in survival and virulence of Cryptococcus neoformans.

Physiological role for phosphatidic acid in the translocation of the novel protein kinase C Apl II in Aplysia neurons.

Birth of normal offspring from mouse eggs activated by a phospholipase Czeta protein lacking three EF-hand domains.

Expression and evolution of the phosphoinositide-specific phospholipase C gene family in Arabidopsis thaliana.

Multiple roles of phosphoinositide-specific phospholipase C isozymes.

Computational active site analysis of molecular pathways to improve functional classification of enzymes.

Neogenin-mediated hemojuvelin shedding occurs after hemojuvelin traffics to the plasma membrane.

Difference in Ca2+ oscillation-inducing activity and nuclear translocation ability of PLCZ1, an egg-activating sperm factor candidate, between mouse, rat, human, and medaka fish.

NPHS3: new clues for understanding idiopathic nephrotic syndrome.

B2 receptor-mediated dual effect of bradykinin on proximal tubule Na+ -ATPase: sequential activation of the phosphoinositide-specific phospholipase Cbeta/protein kinase C and Ca2+ -independent phospholipase A2 pathways.

Activation of human phospholipase C-eta2 by Gbetagamma.

High-performance liquid chromatographic assay with ultraviolet spectrometric detection for the evaluation of inhibitors of phosphatidylinositol-specific phospholipase C.

Role of helix B residues in interfacial activation of a bacterial phosphatidylinositol-specific phospholipase C.

Mutations in PLCE1 are a major cause of isolated diffuse mesangial sclerosis (IDMS).

Activation of extracellular-signal regulated kinase (ERK1/2) by fluid shear is Ca(2+)- and ATP-dependent in MC3T3-E1 osteoblasts.

ATP release by way of connexin 36 hemichannels mediates ischemic tolerance in vitro.

Multiple point mutations in virulence genes explain the low virulence of Listeria monocytogenes field strains.

Phospholipase C-epsilon regulates epidermal morphogenesis in Caenorhabditis elegans.