Latest papers

Fluvastatin inhibits mast cell degranulation without changing the cytoplasmic Ca2+ level

An uncultivated crenarchaeota contains functional bacteriochlorophyll a synthase.

Identification of secondary targets of N-containing bisphosphonates in mammalian cells via parallel competition analysis of the barcoded yeast deletion collection.

Chemical mediators and the resolution of airway inflammation.

Protein farnesyltransferase-catalyzed isoprenoid transfer to peptide depends on lipid size and shape, not hydrophobicity.

Mechanisms of the action of zoledronic acid on human MG-63 osteosarcoma cells.

Isolation and characterization of the gene associated with geosmin production in cyanobacteria.

Rab geranylgeranylation occurs preferentially via the pre-formed REP-RGGT complex and is regulated by geranylgeranyl pyrophosphate.

Statins activate GATA-6 and induce differentiated vascular smooth muscle cells.

Initiation of rubber biosynthesis: In vitro comparisons of benzophenone-modified diphosphate analogues in three rubber-producing species.

Caged protein prenyltransferase substrates: tools for understanding protein prenylation.

Simvastatin-induced endothelial cell detachment and microparticle release are prenylation dependent.

Identification of farnesyl pyrophosphate and N-arachidonylglycine as endogenous ligands for GPR92.

Quantitative determination of farnesyl and geranylgeranyl diphosphate levels in mammalian tissue.

Characterization of two beta-1,3-glucosyltransferases from Escherichia coli serotypes O56 and O152.

Specific partial reduction of geranylgeranyl diphosphate by an enzyme from the thermoacidophilic archaeon Sulfolobus acidocaldarius yields a reactive prenyl donor, not a dead-end product.

LDL induces parathyroid hormone-related protein expression in vascular smooth muscle cells: Modulation by simvastatin.

X-ray crystallographic studies of substrate binding to aristolochene synthase suggest a metal ion binding sequence for catalysis.

Redirection of flux through the FPP branch-point in Saccharomyces cerevisiae by down-regulating squalene synthase.

Inhibition of rho family functions by lovastatin promotes myelin repair in ameliorating experimental autoimmune encephalomyelitis.