Latest papers

AIP-1 ameliorates beta-amyloid peptide toxicity in a Caenorhabditis elegans Alzheimer's disease model.

Farnesylation of pex19p is required for its structural integrity and function in peroxisome biogenesis.

Getting a handle on protein prenylation

Statins decrease dendritic arborization in rat sympathetic neurons by blocking RhoA activation.

Chemistry and biosynthesis of isoprenylated flavonoids from Japanese mulberry tree.

Cytotoxic Prenylated Flavonoids from the Stem Bark of Maackia amurensis

Osteogenic activities of genistein derivatives were influenced by the presence of prenyl group at ring A.

TrkB-mediated activation of geranylgeranyltransferase I promotes dendritic morphogenesis.

A mutation in Rab38 small GTPase causes abnormal lung surfactant homeostasis and aberrant alveolar structure in mice.

Vesicular trafficking in osteoclasts.

[A-type lamins and progeroïd syndromes : persistent farnesylation with dramatic effects]

Rab geranylgeranylation occurs preferentially via the pre-formed REP-RGGT complex and is regulated by geranylgeranyl pyrophosphate.

Constitutively active Rheb induces oncogenic transformation.

Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation.

Simvastatin-induced endothelial cell detachment and microparticle release are prenylation dependent.

Intestinal absorption mechanisms of prenylated flavonoids present in the heat-processed Epimedium koreanum Nakai (Yin Yanghuo).

Interacting targets of the farnesyl of transducin gamma-subunit.

Biphasic requirement for geranylgeraniol in hippocampal long-term potentiation.

Growth inhibition of colon cancer cells by polyisoprenylated benzophenones is associated with induction of the endoplasmic reticulum response.

A new cytotoxic prenylated dihydrobenzofuran derivative and other chemical constituents from the rhizomes of Atractylodes lancea DC.