Latest papers

A novel N-alkylated prodigiosin analogue induced death in tumour cell through apoptosis or necrosis depending upon the cell type.

Elucidation of the Streptomyces coelicolor pathway to 2-undecylpyrrole, a key intermediate in undecylprodiginine and streptorubin B biosynthesis.

Antibacterial colorants: characterization of prodiginines and their applications on textile materials.

Structural insight of the role of the Hahella chejuensis HapK protein in prodigiosin biosynthesis.

A prodigiosin analogue inactivates NADPH oxidase in macrophage cells by inhibiting assembly of p47phox and Rac.

Role of interleukin-2 regulated proteins in immunosuppression by the N-alkylated prodigiosin analogue.

Prodigiosin isolated from Hahella chejuensis suppresses lipopolysaccharide-induced NO production by inhibiting p38 MAPK, JNK and NF-kappaB activation in murine peritoneal macrophages.

Undecylprodigiosin selectively induces apoptosis in human breast carcinoma cells independent of p53.

Anticancer and immunosuppressive properties of bacterial prodiginines.

Pseudovibrio denitrificans strain Z143-1, a heptylprodigiosin-producing bacterium isolated from a Philippine tunicate.

Role of adenosine kinase in the control of Streptomyces differentiations: Loss of adenosine kinase suppresses sporulation and actinorhodin biosynthesis while inducing hyperproduction of undecylprodigiosin in Streptomyces lividans.

The anticancer agent prodigiosin induces p21WAF1/CIP1 expression via transforming growth factor-beta receptor pathway.

Mechanisms of prodigiosin cytotoxicity in human neuroblastoma cell lines.

Virulence and prodigiosin antibiotic biosynthesis in Serratia are regulated pleiotropically by the GGDEF/EAL domain protein, PigX.

Tautomeric equilibria in phenolic A-ring derivatives of prodigiosin natural products.

Prodigiosins: a novel family of immunosuppressants with anti-cancer activity.

Inhibition of quorum sensing in Serratia marcescens AS-1 by synthetic analogs of N-acylhomoserine lactone.

Chloride anion transport and copper-mediated DNA cleavage by C-ring functionalized prodigiosenes.

Phosphorylated AbsA2 negatively regulates antibiotic production in Streptomyces coelicolor through interactions with pathway-specific regulatory gene promoters.

Identification of a red-pigmented bacterium producing a potent anti-tumor N-alkylated prodigiosin as Serratia marcescens