Latest papers

A vanadium/aspirin complex controlled release using a poly(beta-propiolactone) film. Effects on osteosarcoma cells.

In vivo antibody response and in vitro CTL activation induced by selected measles vaccine candidates, prepared with purified Quil A components.

beta-Propiolactone: viral inactivation in vaccines and plasma products.

A model to study the effects of a viral inactivator (beta-propiolactone) on DNA ligation and gene expression in E. coli and Cos cells.

Kinetics of induction of DNA damage and lacZ gene mutations in stomach mucosa of mice treated with beta-propiolactone and N-methyl-N'-nitro-N-nitrosoguanidine, using single-cell gel electrophoresis and MutaMouse models.

beta-Propiolactone.

A bioassay for interferon type I based on inhibition of Sendai virus growth.

[Weak carcinogen protects against the effect of strong carcinogen not requiring the metabolic activation].

Inactivation of viruses by beta-propiolactone in human cryo poor plasma and IgG concentrates.

Differential growth response to exogenous calcium in normal and carcinogen-exposed primary human keratinocyte cell cultures.

The genetic toxicity of time: importance of DNA-unwinding time to the outcome of single-cell gel electrophoresis assays.

Effect of beta-propiolactone treatment on the complement activation mediated by equine antisera.

Enhanced TNF alpha production by monocytic-like cells exposed to dengue virus antigens.

Tissue-specific induction of mutations by acute oral administration of N-methyl-N'-nitro-N-nitrosoguanidine and beta-propiolactone to the Muta Mouse: preliminary data on stomach, liver and bone marrow.

Beta-propiolactone UV inactivated clotting factor concentrate is the source of HIV-infection of 8 hemophilia B patients: confirmed.

A multistep procedure for the chemical inactivation of human immunodeficiency virus for use as an experimental vaccine.

Evaluation by polymerase chain reaction on the effect of beta-propiolactone and binary ethyleneimine on DNA.

Inactivation of DNA by beta-propiolactone.

Psoralen treatment of adenovirus particles eliminates virus replication and transcription while maintaining the endosomolytic activity of the virus capsid.

Synthesis and biological activity of new 3-hydroxy-3-methylglutaryl-CoA synthase inhibitors: 2-oxetanones with a meta-substituent on the benzene ring in the side chain.