Latest papers

The synthesis of UDP-N-acetylglucosamine is essential for bloodstream form trypanosoma brucei in vitro and in vivo and UDP-N-acetylglucosamine starvation reveals a hierarchy in parasite protein glycosylation.

PSGL-1 from the murine leukocytic cell line WEHI-3 is enriched for core 2-based O-glycans with sialyl Lewis x antigen.

A hierarchical network controls protein translation during murine embryonic stem cell self-renewal and differentiation.

Translational control: a new dimension in embryonic stem cell network analysis.

Calmodulin-like protein enhances myosin-10 translation

The signal peptide of the mouse mammary tumor virus Rem protein is released from the endoplasmic reticulum membrane and accumulates in nucleoli.

Ca2+-operated transcriptional networks: molecular mechanisms and in vivo models.

[Disease-oriented enzymology in D-amino acid metabolism].

N-glycosylation as novel strategy to improve pharmacokinetic properties of bispecific single-chain diabodies.

Peters Plus syndrome is a new congenital disorder of glycosylation and involves defective Omicron-glycosylation of thrombospondin type 1 repeats.

Phosphodiesterase 5 inhibitors and cystic fibrosis: correcting chloride channel dysfunction.

Glyoxalase-1 prevents mitochondrial protein modification and enhances lifespan in Caenorhabditis elegans.

Preclinical evidence that sildenafil and vardenafil activate chloride transport in cystic fibrosis.

Topology of molecular machines of the endoplasmic reticulum: a compilation of proteomics and cytological data.

Inverse correlation between the extent of N-glycan branching and intercellular adhesion in epithelia. Contribution of the Na,K-ATPase beta1 subunit.

A necessary and sufficient determinant for protein-selective glycosylation in vivo.

Inefficient glycosylation leads to high steady-state levels of actively degrading cardiac triadin-1.

Site-specific modification and PEGylation of pharmaceutical proteins mediated by transglutaminase.

In this issue: basic immunology and translational research on NF-kappaB.

A subgroup of plant aquaporins facilitate the bi-directional diffusion of As(OH)3 and Sb(OH)3 across membranes.