Latest papers

Meet me halfway: when genomics meets structural bioinformatics.

Synthesis of all-hydrocarbon stapled α-helical peptides by ring-closing olefin metathesis.

Biospeciation of tungsten in the serum of diabetic and healthy rats treated with the antidiabetic agent sodium tungstate.

Entomology: Royal aspirations.

Dramatic destabilization of transmembrane helix interactions by features of natural membrane environments.

Toward functional carboxylate-bridged diiron protein mimics: achieving structural stability and conformational flexibility using a macrocylic ligand framework.

Macromolecular crowding fails to fold a globular protein in cells.

Modulation of contact order effects in the two-state folding of stefins A and B.

On the terminal homologation of physiologically active peptides as a means of increasing stability in human serum--neurotensin, opiorphin, B27-KK10 epitope, NPY.

Role of Hydration in Collagen Recognition by Bacterial Adhesins

Systematic Examination of Polymorphism in Amyloid Fibrils by Molecular-Dynamics Simulation

Complex ion effects on polypeptide conformational stability: chloride and sulfate salts of guanidinium and tetrapropylammonium.

Alteration of negatively charged residues in the 89 to 99 domain of apoA-I affects lipid homeostasis and maturation of HDL.

βTrCP regulates BMI1 protein turnover via ubiquitination and degradation.

Human Mutations in NDE1 Cause Extreme Microcephaly with Lissencephaly

The A391E mutation enhances FGFR3 activation in the absence of ligand

Effect of protein–surfactant interactions on aggregation of β-lactoglobulin

Lesson from the stoichiometry determination of the cohesin complex: a short protease mediated elution increases the recovery from cross-linked antibody-conjugated beads.

Characterisation of factor IX with a glycine-to-valine missense mutation at residue 190 in a patient with severe haemophilia B.

Conformational Conversion during Amyloid Formation at Atomic Resolution